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Extracting the Secrets of Secondary Metabolites
… for growth yet essential for survival, may now be easier to characterize following a proof-of-concept study in which … Interspaced Short Palindromic Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due to the lack of robust tools …
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Virus Discoveries that Keep Getting Bigger
… Sequence-based studies — from metagenomics to single-cell work — have quickly accelerated understanding … viruses. Now categorized in their own phylum,  Nucleocytoviricota , these giant viruses boast larger genomes than … researchers have used culture-independent approaches to gain insight into the  genomes of giant viruses. In a new …
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Nigel Mouncey
… the DOE Joint Genome Institute in 2017 as the fourth Director in its 27-year history. He has a wealth of managerial experience from almost 20 years in the Industrial Biotechnology private sector, as well as research expertise in secondary metabolites … Secondary Metabolites Program head as well as our JGI Director. Click to learn more about the program's areas of focus, …
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Promoting the Power of Viral Metagenomics
… . The following guest piece was written by Call, a postdoctoral fellow in the JGI Microbiome Data Science Group led by … early 2020, people all over the world have been forced to confront the awesome power that viruses have to affect nearly every aspect of our daily lives.  But for …
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Simon Roux
… Dr. Roux joined the JGI in 2017 to lead viral genomics research as part of the Metagenome … include the development of novel computational tools to identify virus sequences, the design of new experimental … al., 2023. iPHoP: An integrated machine learning framework to maximize host prediction for metagenome-derived viruses …
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Supporting Global Research into Actinomycetes
… ActinoBase offers a public portal of insight into special groups of actinobacteria Streptomyces is more than just a funny word. The 500 species … understanding of the bacteria potentially holds the key to discovering new antiviral medicines and treatments for …
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SPRUCE-ing Up Science
… is now applying his internship lessons on presentations to peatlands Travis Lawrence sits in his backyard in … from northern California and one of the first students to participate in the DOE Joint Genome Institute (JGI)-UC … Merced internship program, Lawrence is now a postdoctoral researcher at the Oak Ridge National Laboratory …
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JGI Contributes Eight to 2023 Highly Cited Researchers list
… Congratulations to the 2023 Highly Cited Researchers from the JGI recognized … Those from the JGI whose publications rank in the top 1% by citations for field and publication year are: Igor … Microbiology) These researchers have contributed to several articles in the past year, including: Nikos …
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Training the Next Generation of Talent
… was back on campus at the University of California, Merced to start orientation as a first-year graduate student in the … Olmstead saw a few familiar faces, one of them belonged to his research adviser Axel Visel. Both Visel and another … genome research and apply experimental and computation tools to solve research problems. In Visel’s group, Olmstead …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… researchers described how the viruses repeatedly attempted to infect and destroy the host archaea – and how the  … but the viruses that infect Altiarchaea cause the cells to burst. This action triggers subsurface carbon cycling, … which can serve as a food source for other microbes into the environment. Summary In J. R. R. Tolkien’s “The Lord …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… are abundant and yet exceptionally small, with mini genomes to match. As a result, they cannot process all of the chemicals they need to survive. To fill in their nutrient gaps, they must latch onto a … was supported in part by the Allen Distinguished Investigator Program, through The Paul G. Allen Frontiers Group, the …
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Fungal Friends or Foes in Plant Roots
… boost yields for both food and for candidate bioenergy feedstock crops. Summary A plant is like an office building, its roots are akin to the ground floor lobby. People walking into the lobby have many reasons for being there, but they’re … relevant Dikaria”. This work was supported by funds to S.Hac from a European Research Council starting grant …
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