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A One-Stop Shop for Analyzing Algal Genomes
… complex and difficult to sequence and understand. A team of researchers led by Algal Genomics Program lead Igor … Lab), have unveiled PhycoCosm in the Nucleic Acids Research journal. The genome portal reinforces the JGI’s new … sequenced algal genomes — many sequenced by the JGI — so researchers can easily explore the evolutionary and …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… human chromosomes: Lawrence Berkeley National Laboratory researchers were studying Chromosome 5, which contains about … and diabetes mellitus. Los Alamos National Lab researchers investigated Chromosome 16, which contains about … 1997. Over the next seven years, and in collaboration with researchers at the Stanford Human Genome Center, JGI staff …
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Extracting the Secrets of Secondary Metabolites
… to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE technologies. While … Recombinase-Assisted Genome Engineering) is a technique researchers can use to integrate large genetic payloads … into diverse microbes. Combining CRAGE with CRISPR provides researchers with a powerful addition to their toolkit to …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… heavily invested in being the bridge to help scientists and researchers achieve their analysis goals. Offering this tool … cell’s genome is missing from the final assembly. So while researchers are confident all the DNA sequences came from … from complete.  In 2021 , scientists at St. Jude Children’s Research Hospital developed a new method of genome …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… to energy, are made up heavily of sphagnum mosses.  New research identifies sex chromosomes in the plant and … growth rates, decomposition, and carbon sequestration. Researchers wanted to better understand how sphagnum adapts … help preserve peat bogs in the wake of climate change. Researchers at the U.S. Department of Energy Joint Genome …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… of meta-analyses boosted by AI and Machine Learning — JGI researchers and collaborators work to create FAIR datasets … with tracings of stable, heavy isotopes, SIP allows researchers to go beyond understanding which microbes are … swapped for the heavier, non-radioactive isotope Carbon-13, researchers can then safely follow the path of that modified …
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Supercharging SIP in the Fungal Hyphosphere
… novel interactions between bacteria and fungi The Science Researchers have successfully automated aspects of a … Applying this method to the study of a particular fungi, researchers identified novel interactions between bacteria … Later, their DNA can be tested for the isotope, which tells researchers which microorganisms used the labeled substance …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… made strides in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In … reported in  Applied and Environmental Microbiology , the researchers engineered root bacteria  Pseudomonas  and … demonstrate that CRAGE is all the rage – and interested researchers can now request this capability. Scientists can …
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Fishing for Novel Cellulose Degraders
… specific catches. A similar technique has been developed by researchers led by Tanja Woyke at the U.S. Department of … potential applications to industrial processes. Summary JGI researchers developed a function-driven, single-cell screen … several microbes from known cellulose-degrading groups, the researchers also hooked and were able to reconstruct a …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… the complex organic matrix of the forest floor, a team of researchers have found that there is a striking division of … for User Science (FICUS) initiative, which allows researchers to integrate the expertise and capabilities of … Sports of the Czech Republic (LTT17022). A portion of this research was per- formed under the Facilities Integrating …
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Fungus Fuels Tree Growth
Researchers start pinning down how a fungal symbiont spurs … plant growth hormones. One other tidbit that caught the researchers’ attention is that the poplar cuttings had … sponsored by the Office of Biological and Environmental Research at the United States Department of Energy (DOE) …
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The Power of One, Amplified
… cell genomics complements metagenomics studies. The Science Researchers demonstrated the value of conducting large-scale … Continuing explorations into this unique environment, researchers from the University of Calgary and the U.S. … heterogeneity of uncultivated microbes will provide researchers the ability to capture the fine-scale variation …
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