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A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the …

The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help them digest their last leafy meal. In their evolutionary history, these fungi branched off early from aerobic fungi, which can breathe oxygen — …

… a microbial mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But what trends govern those … interactions? Do generalist viruses run rampant, capable of infecting different host species? Or, do they tend to …

Bacterial enzymes play second fiddle to those from fungi when it comes to breaking … analyzing the enzymes present in the complex organic matrix of the forest floor, a team of researchers have found that there is a striking division …

… 2023 marked a decade since the inception of the flagship internship program between the DOE Joint Genome Institute (JGI) and University of California (UC), Merced. What started with 2 interns in …

… team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director …

Team develops a computational pipeline to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring polar bears in winter scenes that came with crayons in various shades of white. To researchers searching for sequences of RNA …

More than 20 UC Merced students have contributed to the research of 13 JGI scientists since the program’s inception. In 2014, … Science Programs Deputy Axel Visel teamed with University of California (UC), Merced assistant professor Suzanne Sindi …

Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key role in determining the composition of the Earth’s atmosphere and regulating the global climate …

… to link genomes with environments to understand how webs of microbes cycle carbon and sustain biomes via the … Click to learn more about the program's areas of focus, major initiatives and more.  … B.S. in Chemical Engineering, … … Metabolomics Science Program … Education … Selected Publications … Awards and Honors …

Dr. Udwary serves as a computational biologist for JGI’s Secondary Metabolites group. His research interests lie in use and development of bioinformatics tools for elucidation of biosynthetic gene … (1996) … List available on Google Scholar … Education … Publications …

Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, particularly actinomycetes. … technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … Mol. Microbiol. 87, 1223-1236. PubMed … Education … Publications …