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JGI at the AGU Fall Meeting
… This year the AGU Fall Meeting, with the theme “Science is Society,” hosts sessions in New … (all times in PST unless otherwise noted): December 7   9:15am PT (online) Town Hall on the role of user facilities in …
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Better Genome Editing for Bioenergy
… in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help … genes were essential to  Y. lipolytica . They identified 1,377, or 17.5 percent, of  Y. lipolytica ’s genes to be required for … work was supported by DOE Joint Genome Institute grant  CSP-503076 (IW, HA, and MB) and NSF  1706545 (IW). HA and JW …
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Streamlining Regulon Identification in Bacteria
… technology could speed up associating transcription factors with their target genes. The Science Regulons are a group of … sequencing, they were able to identify the target genes of 11 sigma factors in Streptomyces coelicolor . The Impact As … of whole transcriptomes, and the third is determining the 5’-ends by 5’-end sequencing, from which those promoter …
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Cultivating Symbiotic Antarctic Microbes
… Impact The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in environmental … to that of a free-living organism. First discovered in 2011, Nanohaloarchaea are part of the DPANN (Diapherotrites, … dhesion and  r estriction  e ndonuclease domains—of up to 8,500 amino acids in length. These were actively synthesized …
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Extracting the Secrets of Secondary Metabolites
… secondary metabolites, those molecules not essential for growth yet essential for survival, may now be easier to … in overcoming this obstacle when it hit the scene in 2019. Now, that power is poised to grow exponentially by … then employ CRISPR in a variety of microbial hosts. Summary Photorhabdus luminescens proves fatal to insects. It is …
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JGI@25: Building a Better Bean
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that … the common bean. That work was published online June 8, 2014 in the journal Nature Genetics . “Common beans are a …
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Researching and Solving Real-World Problems with the 2023 JGI-UC Merced Interns
… This year’s cohort for the JGI-UC Merced Internship Program was brimming with excitement and determination as they came … Andrew Lin and mentor Vy Duong, Understanding Key Genes in Photosynthesis Ravikiran Madichetty and mentors TBK Reddy … and the fact that I got to do a project involving over 12,000 fungal genomes was just really, really exciting for …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that … relative of SOD is P. infestans , responsible for the mid-19th century Irish potato famine.   Shortly before the … and mechanisms of pathogenesis . Science. 2006 Sep 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of …
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Len Pennacchio
… on applying state-of-the-art molecular methods to address wide-ranging questions existing in biology. He holds joint … at UC Berkeley. Dr. Pennacchio received his Ph.D in 1998 from the Department of Genetics at Stanford University … Fellow where he identified a novel apolipoprotein (ApoA5) involved in human and mouse triglyceride metabolism. He …
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