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DNA Synthesis Program
… bioenergy solutions.  The program has been a pioneering effort in functional genomics since 2012, with a focus on … by synthesizing genes, pathways, and whole chromosomes for bioenergy and bioproduct applications. The program has … gene synthesis, combinatorial pathway design, and efforts to refactor entire chromosomes, such as a yeast …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… at the JGI’s history, from its beginnings in the sequencing for the Human Genome Project out to the future of the … Genomics Building, the JGI’s home at Berkeley Lab. Like the mural, the JGI’s accomplishments over 25 years span … program manager for the Joint Genome Institute Dan Drell, like Ari Patrinos, was around for the JGI’s inception as …
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Complete genome sequence of the halophilic bacterium Spirochaeta africana type strain (Z-7692T) from the alkaline Lake Magadi in the East African Rift
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Engagement Webinar: What Can You Do With An Approved CSP Functional Genomics Call Proposal?
… the Community Science Program’s  Functional Genomics call for proposals .  On July 8, JGI’s DNA Synthesis Science … the Community Science Program’s  Functional Genomics call for proposals . The proposal call is open year-round, but … July 30 will be included in the next review. “So webinars like this didn’t really fully exist back then,” said Hal …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… by minimizing flood risks and filtering water. Peat formed there over thousands of years sequesters more carbon … vegetation types in the world combined. Harvesting peat for energy has been increasingly discouraged due to … bogs have two distinct zones: Hummocks and hollows flow like hills and valleys, on a smaller scale. Depending on the …
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Complete genome sequence of Thioalkalivibrio paradoxus type strain ARh 1T, an obligately chemolithoautotrophic haloalkaliphilic sulfur-oxidizing bacterium isolated from a Kenyan soda lake
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JGI on the 2020 Highly Cited Researchers List
… highly-cited papers that rank in the top 1% by citations for field and year in the Web of Science.” Less than 6,200 … a gene related to seed dispersal in wild populations for the first time. I-Min Chen ,  Natalia Ivanova ,  Nikos … , and Tanja Woyke  were part of a “big data” mining effort reported in  Nature Biotechnology that led to the …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
PI on this project. “I view the program as an excellent platform to build collaborative research initiatives.” Yasuo … DNA synthesis capabilities that push the frontier in areas like plant secondary metabolites, as well.”  Another paper … and use the data we generated to train machine learning models now publicly available for the research community,” …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… the cells of other organisms. As they infect microbes like bacteria, algae and protists, all kinds of viruses … challenges, characterizing viruses is a key step. For decades, though, many viruses have been somewhat … in soil microbiomes could allow for more accurate ecosystem modeling. In a different vein, characterizing CRISPR defense …
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Mindfully Moving JGI
Walnut Creek, after countless generations of sequencing platforms (up to 120 sequencing machines at maximum) maintained by a workforce that numbered more than 100 at its peak, all the … also, so that the reusable stuff that’s very expensive, like lab equipment and ergonomic equipment – all of that is …
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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
… to directly measure environmental or biological samples (like cell media or lake water) without doing a metabolite … involved? How long does it take to do all the analyses? A:  For the JGI  New Investigator and  Functional Genomics … are strongly sorbed to the clays. Sandy soils are much more likely to work well for metabolomics.  Q:  What tool or …
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Doubling Down on Known Protein Families
… it comes to energy cycles — turning biomass into things like ethanol or hydrogen, or solar energy into hydrogen.  … unique makeup of microbe players and the functions they perform, artificially replicating a whole community is … also tried to hone in on the function of the genes via 3D modeling, and comparing structures of the unknown to those …
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