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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… Innovative technology from this biomanufacturing collaboration is available for licensing. The … in urine to create hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was led by researchers … Contract No. DE-AC02-05CH11231. This research was developed with funding from the Defense Advanced Research Projects …
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    … limitations and the sheer complexity of plant genomes. Now, with improvements to DNA Affinity Purification Sequencing … multi-species dataset enabled by multiplexed barcoding.  Complementing this, researchers have profiled over 160,000 …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… As part of the JGI’s 25th anniversary celebration, the 2022 Annual Meeting featured … Find recordings and recaps of these talks below, starting with Ari Patrinos. The Genomics Arms Race Ari Patrinos , … prove invaluable. By the mid-1990s, the sequencing efforts expanded beyond LANL to include resources from Lawrence …
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Marine Microbe Contains Multitudes
… microbial genomics reveals one bacterial species is made of four ecologically distinct groups with different lifestyles. The Science The bacterium SAR324 is unusually cosmopolitan. In the ocean’s North Pacific Subtropical Gyre, microbes … This research was supported by grants from the Simons Foundation (#329108 and #721223 to EFD) …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… A group led by JGI scientists have made strides in improving and applying a method that allows researchers to quickly … ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the … be engineered. “Piloting access to this emerging technology with JGI users will enable us to assess CRAGE’s impact, …
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The More the Merrier: Making the Case for Plant Pan-genomes
… system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the merrier,” with respect to their genomes. In their base state, they are … plants; at least once during their evolution, the genomes of flowering plants multiply. Over time, plants lose many …
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Fungus Fuels Tree Growth
… start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.     The Science … fungus  Mortierella elongata enjoys a dual lifestyle; it can thrive in the soil as a saprophyte, living off decaying … root cells. The fungus is almost always found among and within poplar trees, and in an effort to understand its …
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Dan Rokhsar
… the founding Associate Director for Computational Genomics, and led the computational efforts directed towards the sequencing, annotation, and analysis of three human chromosomes. After successful completion of … Publications … Director, Berkeley NHGRI Training Program in Genomics and Computational Biology …
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Ian Blaby
… where he leads three groups focused on HTP DNA design and assembly, strain engineering and bioinformatic tool … National Laboratory where he focused on functional genomics of phototrophs. Through this and post-doctoral positions at University of Florida and UCLA he has worked with a wide range of eukaryotic algae, archaea and bacteria …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
… Gardeners and farmers around the country recognize that crop varieties … Innovation , and the  Joint BioEnergy Institute —have expanded the network of common gardens and are exploring … the crop for additional end products. The genetic diversity within this set of plants, each with a fully-sequenced …
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Defining a Pan-Genome for Antarctic Archaea
… Analysis of haloarchaeal metagenomes broadens understanding … on Antarctica distinct and unique. In collaboration with the DOE Joint Genome Institute, a DOE Office of Science … of the strain variation appeared related to defense against viruses. Experiments infecting H. lacusprofundi with an …
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Identifying the Microbial Cleanup Crew at a Superfund Site
… Analysis reveals the microbial community involved in a … PCE (perchloroethylene) found its way into the groundwater of several communities in New Mexico via leakage from a … JGI’s  Integrated Microbial Genomes and Microbiomes (IMG/M) system. For example, the team has since identified  …
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