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… shared by most living creatures for energy, growth and reproduction—most organisms produce a set of "secondary … secondary metabolites are produced by groups of genes known as biosynthetic gene clusters (BGCs.) As reported in the … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …

… researchers confirm microbial diversity is wilder than ever. Imagine researchers exploring a dark room with a flashlight, only able to clearly identify what falls within … also tried to hone in on the function of the genes via 3D modeling, and comparing structures of the unknown to those …

… (JGI). Researchers from the DOE Systems Biology Knowledgebase (KBase), the National Microbiome Data Collaborative (NMDC), and Berkeley Lab Biosciences Area are also co-located in the IGB. Vision  Lead genomic innovation for a sustainable bioeconomy. Mission  As a U.S. Department …

… Monitoring Inter-Organism Interactions Within Ecosystems Latest portfolio of … on harnessing genomics to developing sustainable resources for biofuels and bioproducts. Andrew Nelson of the Boyce … are interested in the microbial communities that live on Alaska’s glacially dominated Copper River Delta. They’re …

… Before 2006, Olpidium was one of the many obscure fungi of Chytridiomycota (the “chytrids”).  A … attracted the attention of many mycologists with the two publications of the kingdom-wide, multi-gene phylogeny of … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …

… Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 times … of the Earth’s atmosphere and regulating the global climate for life to flourish. For Guillaume Borrel and Simonetta … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …

… will bring together researchers across major ecosystems and disciplines who are developing and applying laboratory … we will explore cutting-edge advancements in constructing, modeling, and applying these engineered ecosystems across … offering an unparalleled platform for exchanging ideas, forming collaborations, and charting the future of …

… Genome Institute (JGI) staff scientist Simon Roux , who was recently selected as the 2025 recipient of the Microbiome Data Prize by the American Society for Microbiology (ASM). Roux leads the Viral … Virus-Driven Alterations of Microbial Metabolism in Model Soil Ecosystems,” uses a combination of experimental …

… In one article, Micro-Scale Applications head Rex Malmstrom and Metagenome Program head Emiley Eloe-Fadrosh outline more … sorting (FACS) to sort cells into several small pools before sequencing to recover rare microbes. The technique was applied to a recent Nature Communications paper, …

… As SIP experiments shed more light on microbial communities than ever before — especially with the prospect of … high-quality datasets, enabling global insights from modeling, machine learning, and subsequent experiments.  … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …

… to welcome six to the Facilities Integrating Collaborations for User Facilities (FICUS) program for fiscal year 2026, in … with the Environmental Molecular Sciences Laboratory (EMSL) and other national user facilities. Focus areas for these projects include biofuels, biomaterials and …

… Cas14 proteins discovered from JGI’s IMG/M database and biochemically characterized at UC Berkeley and the … led by Jennifer Doudna’s group at the University of California (UC), Berkeley, which is also affiliated with … of Energy under contract no. DE-AC02-05CH11231. The work was supported in part by grants from the Paul Allen Frontiers …