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Better Genome Editing for Bioenergy
… tool that can help scientists engineer organisms for bioenergy applications. Cas9 needs guide RNA to lead it … , a team of researchers likewise honed their tool before felling their research problem: at a genetic level, how … lead Cas9 to make a lethal double-strand DNA break, a dysfunctional sgRNA would be harmless. The team was thus able …
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User Support Analysis Group
User Support Analysis group provides computational analysis for new technology development and JGI user science projects. We perform analysis for diverse experiment types, with main focus areas being genome variation, transcriptomics and epigenomics. Our work varies in scope from the development of …
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The Genomes OnLine Database (GOLD) v.5: a metadata management system based on a four level (meta)genome project classification
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Cultivating Symbiotic Antarctic Microbes
… of an obligate symbiont—entirely dependent on the other for required nutrients—is genome size. The obligate … growth because they had larger genome sizes and their cells were not observed to associate with host cells. In the  Proceedings of the National Academy of …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
For the first time, a team has comprehensively described … kill outright, replicating so thoroughly that they lyse the cell — a process called lytic infection. But some viruses … virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for the 34 …
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Learning to Look
… answer the question, “Where’s Waldo?” readers need to look for a number of distinguishing features. Several characters … Simon Roux, a JGI research scientist in the  Environmental Genomics group . Training the Search Tool Inoviruses are stealth agents that can enter and exit through the cell membrane without lysing the bacterial host. They can …
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An Integrated Dataset to Understand Ecosystem Interaction
Research yields a comprehensive tree and soil dataset for understanding the dynamic relationship between poplar … molecular features to large ecosystem-level processes for the first time. By collecting data from 27 different … managed through human intervention. By leveraging metagenomics, scientists were able to analyze the DNA of …
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Synthetic Biology Informatics Group
Software engineers in the Synthetic Biology Informatics Group develop, deploy, and maintain software that … which provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate … as provide process automation support Research Team    … For further details, please reach out to the Group Lead …
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Picking Up Threads of Cotton Genomics
… , both faculty investigators at the HudsonAlpha Institute for Biotechnology. “The goal has been for all this new … crops. Additionally, cotton is almost entirely made up of cellulose and it is a fiber model to understand the … Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean energy …
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Four Draft Single-Cell Genome Sequences of Novel, Nearly Identical Kiritimatiellaeota Strains Isolated from the Continental Deep Subsurface
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Game On: High School Students Drive Everglades Metagenomics Study
… out to many researchers with the hope of getting support for a research project for his class of 18 juniors.  He got … with the students.  The project provided the students the freedom to define the specifics. It took the coming together … a deeper understanding of both the research process and metagenomics while legitimately contributing to the body of …
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Genomic profiles of four novel cyanobacteria MAGs from Lake Vanda, Antarctica: insights into photosynthesis, cold tolerance, and the circadian clock
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