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The Megadata of Lake Mendota - Part 2: Souped Up Computing
… at the supercomputing that stitches together large datasets with the assembler program MetaHipMer2. Oak Ridge National … — Summit and Frontier — that process terabytes of data with MetaHipMer2. And the National Energy Research … Perlmutter that works at large scale. But nearby the JGI, a cluster called Dori is also capable of running …
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How to Target a Microbial Needle within a Community Haystack
… would allow researchers to focus on specific microbes within metagenome samples and associate their sequences with their roles within their environments. Summary The … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Streamlining Regulon Identification in Bacteria
… technology could speed up associating transcription factors with their target genes. The Science Regulons are a group of … technology, which combines an in vitro transcription assay with RNA sequencing, they were able to identify the target … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Model Fern Reveals Insight into DNA Thievery in Ferns
… Open Green Genomes hits milestone with C. richardii The Science Fern genomes are huge, and … gene transfers from bacteria have all armed the plant with an array of defense mechanisms. The Impact There are … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Extracting the Secrets of Secondary Metabolites
… payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers with a powerful addition to their toolkit to study gene … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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2025 Progress Report
… JGI researchers demonstrate how their laboratory and data …
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JGI-UC Merced Interns Share Their 2021 Experiences
… interns from UC Merced spent eight weeks working virtually with JGI mentors to investigate rigorous research projects, hone … this program’s history, two interns returned to re-engage with their mentors from the previous year and continue … Implementing a Scalable JGI-RQC Pipeline on the Cloud …
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Mapping Heat Resistance in Yeasts
… Genomics Project led by the DOE Joint Genome Institute (JGI), a DOE Office of Science User Facility of Lawrence … grew well; the survivors had their DNA sequenced at the JGI as part of a 2014 Community Science Program project. The …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… National Laboratory (Berkeley Lab). He completed this work with collaborators at the University of Wisconsin-Madison as … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … acids and proteins, as well as recycling nitrogen. Now, with insight into a specific enzyme class that’s important …
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The Power of One, Amplified
… cells harbored mobile genetic elements that were missed within paired metagenome assembled genomes (MAGs), and that dominant populations varied with respect to the amount of within species recombination, … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Finding the Fermenters
… to convert food into energy. However, in environments with little or no oxygen, life had found other ways to … form of metabolism, researchers recently compiled a list of with more than 8,300 organisms from multiple sources, … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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An Automated Tool for Assessing Virus Data Quality
… uncultivated viruses. Following up on those guidelines, JGI researchers have now developed CheckV (pronounced … to recover the genomes of these viruses and associate them with their microbial hosts. However, assembling viral … on one or both sides by genes from the host organism. With the virus-host boundary clearly defined using …
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