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The Surprising Structure of a Shrub Willow Sex Chromosome
… in mammals: a structure that helps correct deleterious mutations. The Impact Shrub willow and its close relative  Populus trichocarpa,  or the poplar tree, are potential biofuel … by the NSF Dimensions of Biodiversity Program (DEB-1542509 to S.D., DEB-1542486 to LBS, and DEB-1542599 to M.O.). …
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Better Genome Editing for Bioenergy
… of the genes in a lipid-prolific yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to identify essential genes and genes that lead to increased lipid … CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, but these …
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JGI@25: Studying Sorghum’s Survival Skills
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of … sorghum’s survival secrets could change not only how we use and grow sorghum, but other important crops as well. In … ) and the grass Brachypodium distachyon ( 2017 ), have identified many more genes than found in the single reference …
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JGI Pitches 2022 Visiting Faculty Program Collaborations
…   On November 3, 2021, the JGI and the Workforce Development & Education … are solicited annually for the summer term (May through August) and selected projects will receive stipend and travel …
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Crops as Tough as World Cup Turf
… from grasses into other crops.  One grass they studied just happened to be the same species that covered World Cup pitches in 2022.                     …
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Draft genome sequence of marine alphaproteobacterial strain HIMB11, the first cultivated representative of a unique lineage within the Roseobacter clade possessing an unusually small genome
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The More the Merrier: Making the Case for Plant Pan-genomes
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … and in the laboratory. “We are fortunate because the progenitor species of  Brachypodium hybridum are … two  B. hybridum types don’t interbreed. “Preliminary artificial crossing experiments between ancestral and recent  …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do anything, they must find a … pairs to generate a matrix of data points.  Applied to 216,015 high-quality virus sequences in the IMG/VR database, …
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Waiting to Respire
… to gain and harness energy. As reported January 28, 2019 in Nature Communications , two research teams … popularizer and communicator (and at one time, the spouse of Lynn Margulis). The information was then used to … and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s Office of …
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Evolution of a Fungal Gene Expression Regulator
… the genome. Many plant pathogens such as the fungi that cause poplar leaf rust, are rich in transposons, which may help the pathogens … of life, they tracked the evolution of 5mC pathways across 528 species. The researchers found that unlike most flowering …
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The Expanding Universe of Methane Metabolisms in Archaea
… insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years … and short-chain alkane oxidation metabolisms. They also identified a set of 38 marker genes that serve as a core set of …
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JGI on the 2021 Highly Cited Researchers List
Nikos Kyrpides Dan Rokhsar Simon Roux Jeremy Schmutz Susannah Tringe Tanja Woyke Below are a few projects each of … (Watch SCGSR fellows Nick Reichart and Ian Rambo talk about their experiences at the JGI.) Igor Grigoriev hosted … developments that will enable researchers to move from identification of microbial novelty to assigning metabolic and …
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