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An Automated Tool for Assessing Virus Data Quality
… fragments and data quality. The Science Through advances in sequencing technologies and computational approaches, … (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … . The Impact The microbes that play key roles in cycling nutrients such as carbon, nitrogen and sulfur are themselves …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
With a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … together, they found most bacterial genomes from water and soil communities were at least 80% complete when studied …
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Interdisciplinary delegation from the University of Duisburg-Essen explores collaborative opportunities with Lawrence Berkeley National Laboratory
A two-day kick-off meeting held at Lawrence Berkeley … as well as microbial ecology with a focus on metabolism and ecosystem health. To facilitate in-depth discussions on …
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Dan Rokhsar
Dr. Rokhsar joined the DOE Joint Genome Institute in 2000 as the founding … directed towards the sequencing, annotation, and analysis of three human chromosomes. After successful completion of … IBM Watson Research Center, Yorktown Heights, NY … Publications … 2018 Marthella Foskett Brown Chair, …
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JGI announces 2024 New Investigator portfolio
The JGI is eager to work and share our tools with a widening circle of researchers. That’s why each year we look for novel …
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JGI@25: Building a Better Bean
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … to their economies. It also plays an important role in soil health through nitrogen-fixation and holds clues for …
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Hiroshi Otani
… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … Characterization of p-hydroxycinnamate catabolism in a soil Actinobacterium. J. Bacteriol. 196, 4293-4303. Otani, … Mol. Microbiol. 87, 1223-1236. PubMed … Education … Publications …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
A group led by JGI scientists have made strides in improving … ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
Researchers looked across many organisms to see that aminotransferase enzymes have evolved mix-and-match … characteristics — creating many different ways of processing nitrogen. To boost crops more efficiently in … past may hold key insights. The way that plants process nutrients has a rich back story — they rely on enzymes that …
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In depth metagenomic analysis in contrasting oil wells reveals syntrophic bacterial and archaeal associations for oil biodegradation in petroleum reservoirs
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2025 NeLLi Symposium
Registration and Agenda Coming Soon!  Hosted by the DOE Joint Genome Institute, the University of Nevada, Las Vegas, and the Desert Research Institute, the …
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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text file, the rows of letters A, T, C and G appearing over and over in a dizzying array of combinations, are unremarkable, save perhaps for the …
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