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Proteome reallocation enables the selective de novo biosynthesis of non-linear, branched-chain acetate esters
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… technology has changed dramatically over the last  25-plus years since the JGI’s inception, making it possible for researchers to get a close look at more ecosystems and organisms than ever before. In 2006, the JGI produced 33 … computing infrastructure and analysis. This way, JGI users — both primary, data-generating users, as well as …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… a computational pipeline to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring … polar bears in winter scenes that came with crayons in various shades of white. To researchers searching for sequences … absence can impact the planet’s nutrient cycles. While most organism’s genetic information is encoded in DNA, with RNA …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… now available to the global research community able to not just analyze but also create DNA sequences mimicking an array of microbial life. By leveraging massive user-generated datasets at the JGI and other publicly … sequences based on the principles it learns from the data about genetic structure — carrying with it the potential …
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A Natural Mechanism Can Turbocharge Viral Evolution
… The Science The first step in the deadly dance between a virus and microbial cell is an embrace. For a virus with a … a specific target on the microbial cell’s membrane. Two decades ago, a team discovered a group of viruses that had … injection of mutations in a particular gene might boost an organism’s fitness. Moreover, the discovery of more than …
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Team Science Reveals Important Protein in Poplar
… With increased lignin and iron, engineered poplar can be used to develop bioproducts for industrial applications. For example, lignin could be used for building materials such as cement or adhesives. … ( https://ror.org/04xm1d337 ), a DOE Office of Science User Facility, and is supported by the Office of Science of …
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Graduate Students Get Thesis Research Opportunity at the JGI
… at one of the DOE national laboratories or national user facilities. As a result of the latest call , a total of … UC Merced School of Natural Sciences. “I’m deeply concerned about climate change and this is a remarkable opportunity to … how engineered environments contribute to greenhouse gases,” Kaze said. “It’s an exciting time in the field …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… and increasing demand for agricultural products.  Sorghum bicolor (L.) Moench is an African grass that adroitly … (UC), Berkeley, UC Agriculture and Natural Resources (ANR), US Department of Agriculture P­­lant Gene Expression Center, … Proceedings of the National Academy of Science the week of December 2, 2019. While sorghum is drought-tolerant, the …
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Data Discovery Tool Helps Identify Microbial Roles within Metagenomes
… developed to help inform scientists and researchers more about the patterns and functions of environmental microbes. Researchers can use the tool to correlate protein annotations with ratios of … frequencies, and an area’s environment hosts particular organisms and metabolisms. This implies that microbiome …
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Expanding Virophage Diversity
… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages are small viruses with double-stranded DNA genomes that co-infect … of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at Lawrence Berkeley National …
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Help from Citrus’ Bitter, Hardier Cousin
… disease-resistance that could prove fruitful for saving Citrus from greening disease. You’ve probably never heard of trifoliate orange. Otherwise known as  Poncirus trifoliata , it’s an evolutionary cousin of the  Citrus genus, which gives us lemons, kumquats, …
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An Addiction Crucial to a Fungus’ Reproduction
… A fungus relies on bacteria to regulate key components of its … machinery The Science To better understand how beneficial organisms (symbionts) are transmitted between host … and a part of the oil-producing Mucoromycotina group, about which little is known. The Cornell team cultivated and …
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