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… di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and interacts with cell signaling networks that … role in regulating microbial cellulose production and biofilm formation, which affects a number of environments, … imaging. The work was enabled in part by a proposal to the DNA Synthesis CSP call , and the results are described in …

… for User Science (FICUS) program, two Department of Energy (DOE) Office of Science national user facilities—the  … computational resources with JGI’s cutting-edge genomics, DNA synthesis and complementary capabilities. Because the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …

… As part of the JGI’s 25th anniversary celebration, the 2022 Annual … sequencing for the Human Genome Project out to the future of the institution. Their talks shed light on how the JGI … time (1986) 98% of the human genome was thought to be junk DNA, so there was quite a bit of resistance to use resources …

… before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. Last year, the JGI surpassed three Petabases of data sequenced — that’s three-quadrillion base pairs of DNA sequence! To meet this “ data tsunami ,” as Kathy Yelick …

… tiny algae. The cold polar oceans give rise to some of the largest food webs on Earth. And at their base are … is displacing these important cold-water communities of algae with warm-adapted ones, a trend that threatens to … isolating the algal communities on filters, they sequenced DNA ‘marker’ gene sequences to identify the microbes. And in …

… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … , researchers led by Hal Alper at The University of Texas at Austin and Michael Jewett of Northwestern … are partnering with Yasuo Yoshikuni and Ian Blaby of the DNA Synthesis Science Program . “This collaboration brings …

… Summer 2025 marked the second year of Alabama A&M University students coming to the DOE Joint … experience funded by a DOE training grant.  Building off the previous year’s project, undergraduate interns … the plants to harvesting the plants and extracting DNA. They also analyzed 16s amplicon data to determine …

… for the global research community. The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) has released … jointgeno.me/2024StrategicPlan .) This plan aligns the DOE Office of Science user facility with broader national … the genomes of individual organisms or environmental DNA, and then using advanced capabilities to understand …

… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … an alternative format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed … are partnering with  Yasuo Yoshikuni and  Ian Blaby of the  DNA Synthesis Science Program . “This collaboration brings …

… Ancient  Chloroflexota s ditched their flagella and other traits when … place: hot spring-dwelling bacteria from the phylum C hloroflexota . Research shows that flagella were lost in other forms of  Chloroflexota that adapted to marine environments … ) conducted by the U.S. Department of Energy Joint Genome Institute …

… the JGI in 2017 to lead viral genomics research as part of the Metagenome Program. His responsibilities include the development of novel computational tools to identify virus sequences, the design of new experimental approaches to link viruses to their … Neri et al., 2023. Expansion of the global RNA virome reveals diverse clades of …