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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE … researchers with a powerful addition to their toolkit to study gene function. As a demonstration, the researchers …
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Help from Citrus’ Bitter, Hardier Cousin
… never heard of trifoliate orange. Otherwise known as  Poncirus trifoliata , it’s an evolutionary cousin of the  … JGI collaborator, are senior authors of the  recent study published in  The Plant Journal.  this study included the discovery of candidate genes that confer …
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Decoding Yellowstone’s Microbial Mats
… cyanobacteria; they began oxygenating Earth over two billion years ago. A team of researchers set out to Yellowstone National Park to study how cyanobacteria are living, communally, in microbial …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … (Berkeley Lab), to fill in these gaps of knowledge. In a study published November 11, 2022, in Cell Genomics , the … with nearly 5,000 publicly available ones and 1,100 metagenome-assembled genomes (MAGs) reconstructed from …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… hitchhikers. These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they … but these symbiotic interactions are difficult to study in the lab. Metagenomics provides new views of these … the microorganisms had a close relationship. Then, using metagenomes and metatranscriptomes generated by the U.S. …
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Viruses Reprogram Cells into Different Virocells
But if the duck gets infected by a virus so that it no longer looks or quacks like one, is it still a duck? For a … The Ohio State University and the University of Michigan studying how virus infections cause significant metabolic … an experimental approach with a marine phage-host model to study virus-host-nutrient interactions. In  their study , …
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Scaling Up Existing Skill Sets
… opportunities in fields ranging from plant-microbe interactions to functional genomics. Hear from five of the Summer 2019 interns, … in industry or academia. It was also a great opportunity to study and learn something totally new during my Ph.D. What …
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An Integrated Dataset to Understand Ecosystem Interaction
… tree and soil dataset for understanding the dynamic relationship between poplar trees and their microbial partners. … Finally, using transcriptomics, researchers were able to study which of the trees were turned on or off in response … Laboratory (Berkeley Lab). All of this information — 318 metagenomes, 98 plant transcriptomes and 314 metabolomic …
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JGI@25: Mapping Switchgrass Traits with Common Gardens
In honor of the JGI's 25th anniversary in 2022, we have … as multiple copies across the chromosomes. In a follow-up study , researchers focused on two types of naturally … JGI Annual Meeting, David Lowry talked about a multi-year study his student conducted involving fungal rust pathogen …
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Astrovirology: how viruses enhance our understanding of life in the Universe
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Extreme dimensions — how big (or small) can tailed phages be?
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Corals in Hot Water Get Help From Their Microbes
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