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Model Fern Reveals Insight into DNA Thievery in Ferns
… well as the evolution of seed plants, the fern’s distant cousin. Ceratopteris richardii, or C-fern, specifically has … (Berkeley Lab) took on the Open Green Genome Initiative in 2018 as part of its Community Science Program. The OGG has … for 85.2% of the C-fern assembly. While they did identify a couple WGD events, these events could not fully …
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Len Pennacchio
Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art molecular methods to … DOE Alexander Hollaender Distinguished Fellow where he identified a novel apolipoprotein (ApoA5) involved in human and … in Genome Biology & Technology (AGBT)” … Education … About the Deputy of Genomic Technologies … Selected …
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Green Algae Reveal One mRNA Encodes Many Proteins
Academy of Sciences , a team of researchers has found numerous examples of polycistronic expression – in which two or … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Berkeley Lab and the Environmental … and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s Office of …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… in mammals: a structure that helps correct deleterious mutations. The Impact Shrub willow and its close relative  Populus trichocarpa,  or the poplar tree, are potential biofuel … by the NSF Dimensions of Biodiversity Program (DEB-1542509 to S.D., DEB-1542486 to LBS, and DEB-1542599 to M.O.). …
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Better Genome Editing for Bioenergy
… of the genes in a lipid-prolific yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to identify essential genes and genes that lead to increased lipid … CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, but these …
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JGI Pitches 2022 Visiting Faculty Program Collaborations
…   On November 3, 2021, the JGI and the Workforce Development & Education … are solicited annually for the summer term (May through August) and selected projects will receive stipend and travel …
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The More the Merrier: Making the Case for Plant Pan-genomes
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … and in the laboratory. “We are fortunate because the progenitor species of  Brachypodium hybridum are … two  B. hybridum types don’t interbreed. “Preliminary artificial crossing experiments between ancestral and recent  …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do anything, they must find a … pairs to generate a matrix of data points.  Applied to 216,015 high-quality virus sequences in the IMG/VR database, …
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Waiting to Respire
… to gain and harness energy. As reported January 28, 2019 in Nature Communications , two research teams … popularizer and communicator (and at one time, the spouse of Lynn Margulis). The information was then used to … and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s Office of …
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Evolution of a Fungal Gene Expression Regulator
… the genome. Many plant pathogens such as the fungi that cause poplar leaf rust, are rich in transposons, which may help the pathogens … of life, they tracked the evolution of 5mC pathways across 528 species. The researchers found that unlike most flowering …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… a computational pipeline to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring … a colored-in page of that book. Published online September 28, 2022, in Cell , a team led by researchers at Tel Aviv … viruses is just the beginning. “I often say that just identifying a sequence as viral is not even half the story.” …
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Tracing the Evolution of Shiitake Mushrooms
… highlight the diversity of white rot fungi in the genus Lentinula   The Science Shiitake mushrooms get their name from the same place they often … from around the world. By complete sequencing of 24 new mushroom genomes, and assembling genomes from 60 …
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