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… make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at … targeted genomic approach would allow researchers to focus on specific microbes within metagenome samples and associate … their sequences with their roles within their environments. Summary The traditional shotgun metagenomics …

… Through advances in sequencing technologies and computational approaches, more and more virus sequences are being recovered and identified from environmental samples (metagenomes). However, the quality and … sequences vary widely. In a previous effort, an international consortium recommended specific guidelines and best …

… clearly. The Science The humble lichen is a superorganism: one being that is actually comprised of two (or more) participants. One is a fungus (usually belonging to the ascomycetes, one of the two main branches of … (for DNA sequencing and assembly); by a three-year subcontract to DA, FL, and FD (for bioinformatics) from a DOE …

… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE … with CRISPR provides researchers with a powerful addition to their toolkit to study gene function. As a …

… viruses. The Science In the last thirty years, in environments all over the world, scientists have discovered giants among viruses. Now categorized in their own phylum,  … of giant viruses came primarily from sampling an environment, then co-culturing isolated viruses in eukaryotic  …

… In honor of the JGI's 25th anniversary in 2022, we have … number of notable achievements that showcase our collaborations and capabilities to enable great science that will help solve energy and environmental challenges. While a hill of beans may not seem to …

… of Science User Facility located at Lawrence Berkeley National Laboratory Berkeley Lab), have taken stock of the … the past three decades, their study assesses what fraction of the microbial diversity we know about, and proposes a … is still unknown.  “We took a deep dive into over 1.8 million bacterial and archaeal genomes to see how much of their …

… strategic plan outlines how the JGI will advance the bioeconomy, leveraging partnerships to advance foundational science, creating opportunities for the global research … the DOE Office of Science user facility with broader national efforts to promote and stimulate a bioeconomy, where …