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Axel Visel
… Programs, he focuses on the development and implementation of strategic initiatives at the JGI. Dr. Visel received his … Hanover, Germany, where he developed novel tools for large-scale in situ gene expression analysis in multicellular … methods for elucidating the gene regulatory landscape of vertebrate genomes, which led to the discovery of …
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Inspiring STEM Careers Through a Hands-on Everglades Microbiome Study
… Journal publication caps JGI pilot project with fledgling Florida … school scientists. The Florida Everglades evokes images of fanboats skimming over swamps, while alligators peer … able to tell the students that the paper was accepted for publication in a reputable scientific journal. It was …
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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
… (CSP) . This includes mass spectrometry-based measurements of primary and secondary metabolites from plants, … analysis.  Q: Can you give us an idea about the scale of an average study? How many samples are typically … Reference: Erbiligin et al.  MAGI: A Method for Metabolite Annotation and Gene Integration . ACS Chem Biol. 2019 Apr …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… Science Altiarchaea are carbon-fixing microbes and targets of multiple viruses in Earth’s deep subsurface. They are abundant representatives of deep subsurface ecosystems. A team of researchers … the Probst lab used to search for and find 13 additional predicted viral  genomes . The team dubbed these viruses …
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A One-Stop Shop for Analyzing Algal Genomes
… data portal allows anyone to freely investigate the genes of more than 100 algae. The Science Interested in the genomes of algae? You now have one place where you can browse the … use PhycoCosm’s genome browser to see their favorite alga’s predicted genes and their organization, and analyze genes in …
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An Addiction Crucial to a Fungus’ Reproduction
… A fungus relies on bacteria to regulate key components of its reproductive machinery The Science To better … both species of organism benefit from association, but was predicted to have evolved from a parasitic interaction with … this mutualistic interaction has on these potential large-scale biodiesel producing fungi. Summary In heritable …
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Accelerating Metagenomics Discoveries with Deep Learning
… insights from metagenomic data. In deep learning, a branch of machine learning, data is passed through algorithms … into multiple interconnected layers. The architecture of these algorithms, inspired by communication networks … protein sequence alignments. He also aims to detect structural similarities in proteins that low sequence …
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Silver age of GOLD introduces new features
… community standards freely available, and enabling large-scale comparative genomics analysis initiatives. GOLD not … sequencing projects carried out at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … a broad range of activities from proposal intake to publication. Information is also obtained and cross-checked …
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JGI@25: Using Team Science to Build Communities Around Data
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … aim is to generate high-quality genome assemblies and annotations for 35 species representing all major … genomes that are both large and complex. The first publication of a genome generated by the OGG initiative — …
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Fungus Fuels Tree Growth
… start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.     The Science The fungus  Mortierella … or mycorrhizal fungi (mutualist symbionts that induce structural changes in plant roots),  M. elongata  doesn’t … the Oak Ridge National Laboratory (ORNL) sponsored by the Office of Biological and Environmental Research at the …
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Webinar: SIP technologies at EMSL and JGI
… Joint Genome Institute (JGI) provide access to a variety of tools that leverage stable isotopes to measure carbon and … The more the better. We want to put at least a microgram of DNA in the tube so you’d need at least 2 micrograms in … want to call it. But NanoSIMS can do that at a really fine scale, and we can also easily measure the 15N at the bulk …
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First Monoploid Reference Sequence of Sugarcane
… . The Science Most species are diploids and have two sets of chromosomes, one from each parent. In contrast, many crops have multiple sets of chromosomes (they are “polyploid”) and their complex … generated is 382 Mb; 25,316 protein-coding gene models were predicted with more than 80 percent found to be colinear to …
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