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How Filamentous Fungi Sense Food
… . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to … Program through a proposal akin to the Encyclopedia of DNA Elements (ENCODE) project, which is aimed at determining … method for identifying protein binding sites in DNA by DNA Affinity Purification, developed and optimized …
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Evolution of a Fungal Gene Expression Regulator
… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures and … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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Short sequence motifs, overrepresented in mammalian conserved non-coding sequences
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Uncovering Novel Genomes from Earth’s Microbiomes
… under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and … National Laboratory (Berkeley Lab), and the  DOE Systems Biology Knowledgebase (KBase) . Metagenomics is the study of … acknowledge the significant efforts to collect and extract DNA from these samples, many of which come from unique, …
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Single-cell RNA sequencing reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress
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Finding the Fermenters
… researchers built an interactive and comprehensive database of fermentative prokaryotes. The Science Most organisms use … process called fermentation. To better understand the range of bacteria and archaea that rely on this form of … National Laboratory (Berkeley Lab), and the DOE Systems Biology Knowledgebase (KBase). They also built an …
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JGI Launches Latest Strategic Plan
… For the Joint Genome Institute, the end of 2018 was marked by a celebration of contributing over one “petabase” – a quadrillion nucleotide bases of DNA sequence to the public data repositories over its now …
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Iron-rich Microbial Mats’ Main Players: Marsarchaeota
… use in number of biotechnological applications. Molecular biology has benefited from heat-stable enzymes derived from … generating thousands to millions of copies of a particular DNA sequence from just a few pieces of DNA. Summary The extreme … The work conducted by the U.S. Department of Energy Joint Genome Institute is supported by the Office …
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Introduction: Sequences and consequences
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Targeted single‐cell sequencing
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JGIota: Sequencing Shiitakes with David Hibbett
… David Hibbett of Clark University fills us in on the kind of decay that makes shiitake mushrooms special. This week, …
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JGIota: The Algae Nicknamed ‘Chlamy’
… why she works on this alga, how researchers managed to sequence its genome, and what it has to teach us about other … a faculty scientist in the Environmental Genomics & Systems Biology Division of the Berkeley Lab Biosciences Area.] …
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