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… “but we really first heard about the JGI synthesis grant during a presentation that [DNA Synthesis Science Head] … the Functional Genomics (formerly DNA Synthesis) call, and he noted the data had driven his lab’s focus on guide … proposals by a consortium. The consortium looked at how different bioenergy relevant plants can produce …

… By leveraging new tools and large-scale data mining, JGI researchers nearly tripled … dataset gives researchers a new foundation for studying how fungi produce and manage energy at the cellular level. … trees built from mitochondrial and nuclear genomes showed strong agreement across the kingdom, confirming that …

… Cas14 proteins discovered from JGI’s IMG/M database and biochemically characterized at UC Berkeley and the … disease. Finally, gene editing is being used to understand how a person’s genetic makeup predisposes them to, or … and Nanohaloarchaea. This work represents an excellent showcase of the unique capabilities provided from the IMG/M …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, Biodesign and pathway engineering Mass spectrometry based metabolomics … Product Description Deliverables Cycle Time FY25 Q1  (median/75th percentile*) DNA Synthesis Constructs <5kb in size …

… Harnessing BER-funded data resources, researchers built an interactive and comprehensive database of fermentative … Most organisms use oxygen to convert food into energy. However, in environments with little or no oxygen, life had … of these microbes. The Impact This study illustrates how the research community brings together the data …

… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to … or 5mC. In many organisms, 5mC is an important piece of how they regulate their genomes, but is not well understood …

… new members to the JGI User Executive Committee (UEC) : Roland Hatzenpichler of Montana State University, Teresa Pawlowska of Cornell … but use-restricted] exist on [the JGI data portal] IMG or how to deal with situations in which they inadvertently …

… Newly developed chemiluminescent biosensors shed light on how bacteria function and colonize diverse environments. The Science Cyclic di-GMP (Guanine Monophosphate) is found in nearly all types of … DE-AC02-05CH11231. This work was supported in part by NIH grants DP2 OD008677 and R01 GM124589, NIH training grant T32 …

… In 2024, the DOE Joint Genome Institute and Alabama A&M University piloted an internship program to bring students to the JGI for … CRISPR Cas9 knockout mutants to observe and investigate how transporter proteins regulate the production of root …

… artificial intelligence to aspects of research questions Another intern summer has closed at the U.S. Department of … Merced cohort consisted of three undergraduate students and eight graduate students, hosted by 18 JGI staff. One of … Jonelle Basso, Heejung Cho Project:  Characterizing how resident phages shape their host phenotype Graduate …

… After studying the mechanism of action of antifungal natural products and their derivatives during her Ph.D. in Microbiology at … Tanja Woyke is the Microbial Science Program Head as well as … more about the program's areas of focus, major initiatives and more.  …

… (DOE) Joint Genome Institute (JGI) is committed to advancing the field of genomics through open access to resources and promoting data sharing to accelerate discovery and … current data policies for gaining a better understanding of how changes may affect data-producing users and other users. …