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Fishing for Novel Cellulose Degraders
… learn more about what microbes are present in any given ecosystem—particularly those that are in low abundances—and … Facility, is supported under Contract No. DE-AC02-05CH11231. The work was supported by a JGI Director’s Science … program (LDRD) entitled ‘Tackling microbial-mediated plant carbon decomposition using “function-driven” genomics’. …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… microorganisms therefore play a critical role in the global carbon cycle, and are of significant interest for their … global carbon cycle and greenhouse gas dynamics, and the engineering of new, optimized methane-making microbes. In … research of these newly found methanogens  in diverse ecosystems with  support from a DOE Established Program to …
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A Grass Model to Help Improve Giant Miscanthus
… without requiring replanting. Miscanthus is especially efficient at this process thanks to a specialized kind of … to and from the rhizome and contribute to the grass’ efficient perennial life cycle. For example, in the fall the … U.S. Department of Energy under Contract No. DE-AC02-05CH11231. The collection of the M. sinensis and M. sacchariflorus …
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Finding the Fermenters
Harnessing BER-funded data resources, researchers built an … researchers recently compiled a list of with more than 8,300 organisms from multiple sources, including the U.S. … Berkeley National Laboratory (Berkeley Lab), and the DOE Systems Biology Knowledgebase (KBase). They also built an …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… company LanzaTech to develop a “cell-free” gene expression system. Developed through the JGI DNA synthesis Community Science Program (CSP) Functional Genomics, the system allows scientists to test enzymatic pathways, which … Clostridium autoethanogenum. The microbe can utilize carbon oxides, including the greenhouse gas carbon dioxide, …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
A nuanced understanding of peat moss drives insight into carbon storage   The Science Boggy peatlands, which hold … majority of the ground cover in peatlands. These boggy ecosystems are acidic and have very little oxygen, which is … protecting these ecosystems. … The work (proposal no. 10.46936/10.25585/60001030) (A.J.S.) conducted by the US …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
JGI’s Integrated Microbial Genomes & Microbiomes (IMG/M) system. “We then looked into many more samples and refined … of sequences, and soon, with trillions. The development of efficient, automated approaches to analyze and classify … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  …
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JGI@25: From Life at the Extremes to Editing Genomes
… lab at UC Berkeley seeks other enzymes in the CRISPR-Cas system. For the past few years they have partnered with … the Integrated Microbial Genomics & Microbiomes (IMG/M) system’s immense collection of publicly accessible … for Some Type V CRISPR-Cas Systems Mol Cell. 2020 Aug 6;79(3):416-424.e5. doi: 10.1016/j.molcel.2020.06.022. Wright AV …
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An Automated Tool for Assessing Virus Data Quality
… genomes . The Impact The microbes that play key roles in cycling nutrients such as carbon, nitrogen and sulfur are themselves regulated by … U.S. Department of Energy under contract no. DE-AC02-05CH11231. This work was also supported the grant #2016/23218-0 …
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Simon Roux
… of viral diversity and virus-host interactions in microbial systems. Through a 2021 DOE Early Career Research Program, … Biology, Université Blaise Pascal, France … Neri et al., 2023. Expansion of the global RNA virome reveals diverse clades … and host dynamics in a high-altitude watershed soil ecosystem. Microbiome 11, 237 Roux et al., 2023. iPHoP: An …
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Tanja Woyke Elected to American Academy of Microbiology
Genomics Department Head for the Environmental Genomics and Systems Biology Division of the Lab’s Biosciences Area since … Lab honorees. Woyke’s research focuses on developing and harnessing single-cell methods to access the genetic … As a result, the giant virus protein space grew from 123,000 to over 900,000 proteins, and virus diversity in this …
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DOE Metrics
… % Goal FY 2025 Total 700.0     8,585     Q1 2025 175 190.304 109% 2,164 2,136 98.7% Q2 2025 175 152.100 87% 2,117 2,112 99.8% Q3 2025 … to planned upgrade of the Laboratory Information Management System (LIMS) and temporary shut down of the sequencing …
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