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Streamlining Regulon Identification in Bacteria
… technology could speed up associating transcription factors with their target genes. The Science Regulons are a group of … various environments are expressed when their functions are needed. Data yielded through RIViT-seq expand the known …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the … announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … be engineered. “Piloting access to this emerging technology with JGI users will enable us to assess CRAGE’s impact, …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… of infecting different host species? Or, do they tend to specialize, infecting just a single host? Another wrinkle … affect their prey in different ways. They have the capacity to kill outright, replicating so thoroughly that they lyse … inside the host’s genome, living quietly and replicating with their host indefinitely. Now, in studying a microbial …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… In  Nature Communications , researchers describe a strategy to recover high value products from human waste. They   genetically modified yeast to efficiently convert elements present in urine to create hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was …
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A Natural Mechanism Can Turbocharge Viral Evolution
… how a fundamental mechanism of evolution allows microbes to adapt to changing environments. The Science The first step in the … a virus and microbial cell is an embrace. For a virus with a “head-tail” morphology, this means using proteins on … B.G.P. was supported by the Marine Biological Laboratory, by the National Science Foundation’s XSEDE computing …
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Thawing permafrost, microbes, and viruses: Gary Trubl — Part 1
… Trubl, a virologist at Lawrence Livermore National Laboratory, wants to understand how viruses impact the release of greenhouse … Arctic permafrost. But to see what they’re doing, he first needs their DNA.   …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… featured speakers who shared a look back at the JGI’s history, from its beginnings in the sequencing for the Human Genome Project out to the future of the institution. Their talks shed light on … Find recordings and recaps of these talks below, starting with Ari Patrinos. The Genomics Arms Race Ari Patrinos , …
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Doubling Down on Known Protein Families
… wilder than ever. Imagine researchers exploring a dark room with a flashlight, only able to clearly identify what falls within that single beam. When it comes to microbial communities, scientists have historically been … User Facility  located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… that showcase our collaborations and capabilities to enable great science that will help solve energy and … environmental challenges. Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a powerhouse. Rumen microbes have the ability to break down hardy plant cell walls and therefore hold …
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Exploring Possibilities: 2022 JGI-UC Merced Interns
… in science. Hear more about what they learned from working with their JGI mentors, what challenges they overcame, and what new skill sets they look forward to taking back to school.  The interns from this cohort and …
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Engagement Webinar: How to Apply for Resources at Multiple DOE User Facilities
… 2021, JGI and the Environmental Molecular Sciences Laboratory (EMSL) co-hosted a JGI Engagement: Accessing Resources at Multiple DOE User Facilities with a Single Proposal webinar, inviting researchers to … contact EMSL and JGI staff to help you appropriately scope a proposal that will be competitive. Q:  Can you …
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Building Sphagnum Genomic Resources
… (CSP), researchers are developing a number of resources to build up Sphagnum as a plant model system focused on … impact on global carbon cycling and climate is estimated to be larger than any other single plant genus. Peatlands … These resources would provide the research community with the ability to address questions such as sphagnum’s …
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