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JGI Launches Latest Strategic Plan
… “petabase” – a quadrillion nucleotide bases of DNA sequence to the public data repositories over its now 20-plus-year history. In 2019, the countdown has begun to the June …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… Trained on environmental data, a new JGI tool more accurately facilitates microbial genome … to draft strands encoded with new proteins or genetic pathways not observed in nature. Because of its enhanced neural network architecture, GenomeOcean has shown improved computational efficiency of its modeling in the …
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When “The Blob” Made It Hotter Under the Water
… marine microbes and by extension, the ocean’s capacity to act as a carbon sink. Summary As global temperatures … a series of geographic coordinates which go from coastal to open ocean waters. Between 2010 and 2016, Hallam and his … User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab), as part of Hallam’s approved proposal …
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JGI@25: Fueling Investigation into Methane-Making Microbes
… that showcase our collaborations and capabilities to enable great science that will help solve energy and … ch allenges. Methane emissions are a massive factor driving climate change. According to the Environmental … chemical compounds that could inhibit microbial methane production. Another effort is in using microbial …
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Building Sphagnum Genomic Resources
… (CSP), researchers are developing a number of resources to build up Sphagnum as a plant model system focused on … regulator since sulfate-reducing microbes prevent methane production by routing the carbon away from methanogens. … found that these species encode a sulfate reduction pathway, but also have genes for sulfide oxidation. The …
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Busting the Unbreakable Lignin
… components   The Science There are three main ingredients to tackle when it comes to breaking down a plant for energy: Cellulose, … use of it, it would change the entire landscape of biomass production and bioproduct engineering. Summary That … DE-AC02–05CH11231 (Lawrence Berkeley National Laboratory), and the Office of Biological and Environmental …
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JGI at the AGU Fall Meeting
… unless otherwise noted): December 7   9:15am PT (online) Town Hall on the role of user facilities in accelerating … Successful Proposals December 9  4:15pm PT (online) Town Hall on how the Facilities Integrating Collaborations … Nitrogen Cycling Microbial Communities and Reduces N2O Production Potential in Sacramento-San Joaquin Delta, …
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Model Fern Reveals Insight into DNA Thievery in Ferns
… Open Green Genomes hits milestone with C. richardii The Science Fern genomes are huge, and incredibly complex — making it difficult to grasp a deeper understanding of fundamental aspects of … resulting comparative framework can inform the efficient production of plant-based biofuels and bioproducts. ( Learn …
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Extracting the Secrets of Secondary Metabolites
… for growth yet essential for survival, may now be easier to characterize following a proof-of-concept study in which … in bacteria, making it difficult to identify which pathway corresponds to which metabolite. Finding a vehicle … of CRAGE, the pairing proved to rapidly confirm enhanced production of 22 metabolites from six biosynthetic gene …
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Gut Fungi: Unexpected Source of Novel Chemicals
… complex compounds — an energetically expensive feat thought to be too costly for them. The Science Anaerobic fungi, which die … O’Malley and her team plan to use genetic tools to boost production and isolate the compounds. Although what … and a gift from the Gordon and Betty Moore Foundation to MAO. A portion of this research was performed under the …
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JGI announces 2024 Functional Genomics awardees
… from reseachers who translate genomic information into biological function. Through our CSP Functional Genomics … leverage the JGI’s DNA synthesis and omics capabilities to enhance understanding of gene and genome function. … and developing high-throughput methods to reveal metabolic pathways that could ultimately enable new or more efficient …
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What Happens Underground Influences Global Nutrient Cycles
… user facilities—the  Environmental Molecular Sciences Laboratory (EMSL) and the  DOE Joint Genome Institute (JGI)—have … Submitted proposals addressed one of the following focus topic areas: Biofuels and bioproducts, Biogeochemistry, and … and soil interact below the ground, influencing the production of microbial greenhouse gases and volatile …
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