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Streamlining Regulon Identification in Bacteria
… sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro … coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions is part of the … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
A group led by JGI scientists have made strides in improving and applying a … is central to our ability to offer host-engineering for our users,” says JGI Director Nigel Mouncey. Using CRAGE, JGI has established a portfolio of microbial …
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Busting the Unbreakable Lignin
The Impact Traditional methods for breaking down biomass use aerobic methods (those using oxygen) to remove lignin and transform the remaining … Research Center. O’Malley is also affiliated with JBEI. The JGI data portals and pipelines helped identify potential …
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An Automated Tool for Assessing Virus Data Quality
CheckV can help researchers assess virus sequence fragments and data quality. The Science Through … technologies and computational approaches, more and more virus sequences are being recovered and identified from … uncultivated viruses. Following up on those guidelines, JGI researchers have now developed CheckV (pronounced …
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Ancient Algae Reveal Secrets of Plant Evolution
… to terrestrial life paves the way for innovations in sustainable agriculture and clean energy. These evolutionary … in marginal lands and with minimal resources. Enabling the use of non-arable land for biomass production — that can be … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Celebrating a Decade of Science through the JGI-UC Merced Genomics Internship Program
… internship program between the DOE Joint Genome Institute (JGI) and University of California (UC), Merced. What started … the summer of 2014 has grown to a total of 75 with the inclusion of the 2023 cohort. Each of them has brought … have a number of initiatives across several different campuses with this being our largest and most successful one. …
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Making a Lichen Together
… time, a team analyzes the transcriptomes of a lichen fungus and alga to understand their partnership more clearly. … comprised of two (or more) participants. One is a fungus (usually belonging to the ascomycetes, one of the two … the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility. Grigoriev and …
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Supercharging SIP in the Fungal Hyphosphere
… have successfully automated aspects of a commonly-used process for studying microbial communities, with … The Impact Stable isotope probing is a long and laborious process — as well as a key way scientists study … HT-SIP is a capability available to request through  the JGI proposal calls . … Work at Lawrence Livermore National …
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The Power of One, Amplified
… sample. Their work showed that single cell genomics can add significant value to the other commonly used culture-independent sequencing approaches including … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Trent Northen
… leadership roles within large DOE-funded research programs using mass spectrometry for energy and environmental … the ENIGMA SFA project. In 2015, he founded what is now the JGI Metabolomics Program to provide advanced metabolomic … Science Program Head at the JGI. Click to learn more about the program's areas of focus, major initiatives and …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… first time, a team has comprehensively described host-virus dynamics in a microbial mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But what trends govern those … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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How Maize Makes An Antibiotic Cocktail
… a family of compounds that protects it against infections — using surprisingly few enzymes. The Science Maize ( Zea mays … scientists have identified at least 15 zealexins, they suspect there are even more to find. Zealexins are produced … as  Sorghum bicolor — a  candidate bioenergy feedstock and  JGI Flagship Plant — could produce at least 15 zealexins. …
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