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… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a … none of that is going to change. It’s only just– we’re just building onto it. So the site is usable now. The website is …

… storage during simulated range shifts of plant-fungal symbionts …

… embargo starting at construct or strain delivery.  Detailed sequence information and constructs are made publicly …

… can provide novel insights into the impact of microbial symbionts and their hosts on ecosystems.   Environmental …

… capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …

… stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … more about some of the background and sort of the reasons why we want to do this. And also to provide a little more … of the fun things that I hope that I can express today is why secondary metabolism is interesting and why it is that …

… And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … And that’s what I really wanted to do. And that’s why I came back to academia. And I set that up. And we …

… our User Program’s Community Science Program, the JGI sequenced and characterized 270 genomes of the Clostridium … To meet these needs, the JGI deploys state-of-the-art sequencers and platforms dedicated to biodesign, single-cell …

… The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … does a beautiful job of marrying synthetic chemistry, building these products that then you can then apply …

… Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of … Profile HMM search across all IMG metagenomes, capturing sequence diversity for proteins of interest. … better understanding of complex ecosystems within hard to sequence and assemble samples, such as those from soil and …

… We focus our efforts on integrating database mining and sequence design with scaling the production of large, … developing methods for converting digital information from sequence databases into biotechnological or environmental …