Search

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these … section. We want to be sure that the PIs can articulate why their work falls within one of these DOE mission areas. …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a … none of that is going to change. It’s only just– we’re just building onto it. So the site is usable now. The website is …

… is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which …

… embargo starting at construct or strain delivery.  Detailed sequence information for constructs are made publicly …

… stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … more about some of the background and sort of the reasons why we want to do this. And also to provide a little more … of the fun things that I hope that I can express today is why secondary metabolism is interesting and why it is that …

… (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any other … annotation, comparative analysis, and interpretation of sequence, metabolomics, and functional genomics data types …

And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … And that’s what I really wanted to do. And that’s why I came back to academia. And I set that up. And we …

We focus our efforts on integrating database mining and sequence design with scaling the production of large, … developing methods for converting digital information from sequence databases into biotechnological or environmental …

The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … does a beautiful job of marrying synthetic chemistry, building these products that then you can then apply …

… can provide novel insights into the impact of microbial symbionts and their hosts on ecosystems.   Environmental …

… through end-to-end automation, and further advancing sequence applications, single cell genomics, DNA synthesis, …

… tool BOOST , which provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …