Search

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … of thought with that. So some people are interested in cave microbial– people are interested in the more extreme …

The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with … exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With … can provide novel insights into the impact of microbial symbionts and their hosts on ecosystems.   Environmental …

… outreach program to get kids interested in microbiology and microbial chemistry. All good stuff, and I hope you enjoy … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

… (Trillions) Operating Hours Goal Actual Total* Actual % of Goal Goal (hours)** Actual Total Actual % Goal FY 2025 … = 91 days; Actual Operation = 24 days due to significant sequencer downtime related to the shelter-in-place. ††† … Q1 – Report on new computational developments for improving microbial, metagenomic, or plant genome assemblies. …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national … at Lawrence Berkeley National Laboratory. The JGI consists of around 280 researchers and support staff in the …

Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … to try and create an open source database of all known microbial natural products. So if you think about natural … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … Group : a research & development group and focused on new technologies and optimizing tools — including strain … automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables …

… constant developments to meet the ever-changing demands of our users. … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic … of microbial communities based on their metagenome sequence, in the context of reference isolate genomes …

… develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic properties … within those genomes. Our aim is to more fully capture microbial and viral diversity, leading to a better …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …