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… — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required … Agreement and Appendix. An Appendix identifies the type of work or specific proposal to be covered under the …

And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … a good catalog of what’s out there so that we can do more comparative analysis and maybe– I don’t know– start to put …

… on genomic science projects that address sustainable biofuel and bioproducts production, leveraging systems-based approaches to unravel functional capabilities of plants, microbes and microbial communities, global carbon … accepted proposals, sequencing, synthesis, metabolomics and analysis will be paid for by the Department of Energy’s …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to … done a lot of work learning about how to use statistical analysis to prioritize both to analyze our bigger system …

… synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission Areas . … accepted proposals, sequencing, synthesis, metabolomics and analysis will be performed by the JGI at no cost to the … large. In most cases where the JGI provides more customized analysis, the JGI also participates in publication of …

… then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against … Pacific Ocean, or in the bay, and be able to do chemical analysis, as well as transcript analysis. And what we’re …

The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … unknown. And so we've done the sequence similallity network analysis where we look for other receptors with sequence …

… (Trillions) Operating Hours Goal Actual Total* Actual % of Goal Goal (hours)** Actual Total Actual % Goal FY 2025 … = 91 days; Actual Operation = 24 days due to significant sequencer downtime related to the shelter-in-place. ††† … 8734 2005 28 33.63 8400 8760 * Reflects actual data due to analysis beyond fiscal year-end close. …

… … DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … to some people more about down the road. Email Nigel! He’ll sequence whatever you want!  [LAUGHTER]  NIGEL MOUNCEY: We … has led a vision for the JGI that sees secondary metabolism analysis and research as a driver for novel technologies …

Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … of system-wide problems. And it’s not just constitutional analysis as a problem, we need corresponding improvements in … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … able to not only purchase their own HPLC to enable faster analysis of their plant extracts, but also establish their … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? …

… … The IMG/M system serves as a community resource for comparative analysis and annotation of all publicly available genomes … of microbial communities based on their metagenome sequence, in the context of reference isolate genomes …