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… technology in order to enhance the quality of single-cell genomes and directly link functional information with individual cells. Research Team    … cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We …

… approaches to assess microbial activity across ecosystems.  By studying microbial communities and their … that could advance our understanding of Earth’s ecosystems. … the complex interactions and functions that shape ecosystems. By decoding the microbial DNA in natural …

… mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate … group attempts to address this question in natural soil ecosystems by combining metagenomics with other omics … these omics data must be complemented with single-cell resolution assays that can be targeted towards specific …

… collaboration with partner organizations such as the DOE Systems Biology Knowledgebase and the National Microbiome … organisms. We provide access to large-scale datasets and analysis tools for genomes, metagenomes, and metabolomics … Building (IGB), a home it shares with the staff of the DOE Systems Biology Knowledgebase (KBase), National Microbiome …

… use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … possess genomes and particle sizes that rival those of cellular organisms. Giant viruses challenge the traditional boundaries between viruses and cellular life, providing unique insights into viral …

… Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there and welcome back for … high altitude! And a lot of us moved on to work in simpler systems, like bacteria, where we figure we can make more … way – the RiPP way, is to make a protein using the normal cellular way of making proteins, with a ribosome. Then, some …

… has gone on, the more we’ve become interested in sort of systems level approaches. So rather than asking one question … of system-wide problems. And it’s not just constitutional analysis as a problem, we need corresponding improvements in … Insider. She talks to lots of great scientists outside of secondary metabolism, and if you like what we’re doing here, …

… have hear over there, with a few more questions specific to secondary metabolites. I hope both versions are worth … to offer you. So there’s a lot of– we also have a lot of analysis pipelines, be it for, again, metagenome, … focus within BER anymore. We really focus on terrestrial ecosystems, but we work in coastal environments, brackish …

… about natural products and the science and scientists of secondary metabolism. Hey everybody, this is Dan with … for a long time about the evolution and natural products systems. This conversation came about because he challenged … about this, he’s very interested in very highly coevolved systems where a microbe becomes a symbiont, for example, of …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … tools to study this complexity, including single-cell and spatial transcriptomics barcode-based genetics … microbiomes hold the amazing ability to influence plant development, fitness and health. This is a dynamic and …

… of complex biological, earth, and environmental systems for energy and infrastructure security. In … Plant, Fungal, Algal, Microbial, Metagenome, Metabolomics, Secondary Metabolites, and DNA Synthesis Science Programs …

… Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Welcome back to Natural … challenges were associated with getting good transformation systems going. That has a lot to do with, well, the fact … Then you have to maybe improve some of your bioinformatic analysis. You don’t want to get clusters that are encoding …