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Mission
… and resources. Our vision is to lead genomic innovation for a sustainable bioeconomy. ALL PROPOSALS must support the … of Energy.   The JGI provides integrated high-throughput sequencing, DNA design and synthesis, metabolomics and … are at the core of many environmental processes, and the genetic makeup of microbial species and communities forms …
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Fine-scale evaluation of two standard 16S rRNA gene amplicon primer pairs for analysis of total prokaryotes and archaeal nitrifiers in differently managed soils
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Natural Prodcast Episode 6: Marc Chevrette
Marc was the Head of Experimental Genomics there, before he decided to leave for graduate school and pursue his … that can’t live without their host. They have no extra genes hanging around, they still dedicate 20-30% of their … it smells like a pine tree. Like there’s no cookie cutter reactions here, we’re really trying to drive discovery. So …
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Natural Prodcast Episode 1: The Primer, Part 1
Takemura, whose voice you’ll hear in a minute – we work for the US Department of Energy Joint Genome Institute, or … what we’re calling a Primer. We wanted to try and give a general audience some of the basics of natural products … by almost all living organisms. So almost all of these reactions are going on in your body. Almost all of these …
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Primer and platform effects on 16S rRNA tag sequencing
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Whole metagenome sequencing and 16S rRNA gene amplicon analyses reveal the complex microbiome responsible for the success of enhanced in-situ reductive dechlorination (ERD) of a tetrachloroethene-contaminated Superfund site
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CSP Functional Genomics
The CSP Functional Genomics call is to enable users to perform state-of-the-art functional genomics research and to … and ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily … form and are reviewed annually. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be …
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Fungal & Algal Program
… vast diversity of fungi and algae to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the … on large-scale sequencing efforts that survey the vast phylogenetic and ecological diversity of fungi and algae, …
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Metagenome Program
The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in … along with their associated viruses and mobile genetic elements. Beyond exploring and characterizing … diversity and metabolic potential, with implications for energy production, environmental sustainability, and …
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DOE Metrics
FY 2025 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours …     2,167     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on 98% of the total … (PIs), Co-PIs, and collaborators. *Unique users are counted once, even though an individual may have several …
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Natural Prodcast Episode 20: Brian Bachmann
I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a …
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Secondary Metabolites Program
… algae and plants. These molecules, which are not essential for fundamental growth, provide critical advantages to the … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … We have developed Regulon Identification by in vitro-sequencing (RIViT-seq) to identify RNA polymerase-sigma …
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