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… group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host … involves both experimental and computational exploration of uncultivated viral diversity, characterization of … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… the secondary metabolism side of things was looking at genomes and seeing where the really hard things to sequence … the Broad that was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods … before. DAN: Yeah, yeah, fun stuff.  MARC: And we call that whole thing, the “chemistry hub”, and that’s centered right …

The mission of the Joint Genome Institute is to serve the scientific … plan is written into a Statement of Work document. … For sequencing projects, once work is under way, raw sequence … more customized analysis, the JGI also participates in publication of results. … Submission … More on Sequencing …

The central mission of the JGI’s Genomic Technologies department is   ensuring … science by generating data in three overarching categories: Sequencing, Synthesis and Metabolomics. Strong internal … cell genomics, DNA synthesis, and metabolomics.   … Deputy of Genomic Technologies …

Science program. It used to actually stand for Community Sequencing Program. Also CSP, same acronym. But as JGI, as a … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we … 100 kb versus 500 kb. In the lab, they’re going to do the whole set at one time. So it’s better to have really more, …

… started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … well. One is to do DNA sequencing. So upon sequencing many genomes, now we don’t have to, as in the past, go randomly … natural product versions of enediyne molecules, there’s a whole bunch of other atoms that can either stabilize the …

… bit more intuition about how you go from the expansion to comparing to the database. Is it like, let’s say I’m drawing … us, we want to hear from you. We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… community at large with access to high-throughput sequencing, synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission Areas . … more customized analysis, the JGI also participates in publication of results. See more details on our Review …

Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … the help of JGI’s DNA synthesis grant. And that having a whole panel of these enzymes allows us to ask the questions … [project] with JGI, how many flavin monooxygenases are you sequencing, sort of along that vein, of if you have one or …

And so these tubules are like tiny monocultures but the whole of the organ which is about the size of your pinky … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … really exciting work on figuring out how to get genomic sequencing data for the fungus garden because it’s more …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … We have developed Regulon Identification by in vitro-sequencing (RIViT-seq) to identify RNA polymerase-sigma … factors and determine their binding sites across multiple genomes. Computational prediction of heterologous …

… before– or kind of around about when the first genome sequencing was done. But natural products– marine natural … five days, seven days, 10 days. And suddenly, you’re then comparing a chemical profile with, let’s say, 100 ions in … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …