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… the JGI by identifying the actual molecules present in an environment that influence system behavior.  Through this … of new molecules and pathways. The JGI Metabolomics Platform delivers rich metabolite profiles from diverse … samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well as different types …

… for example, in terms of the stereochemistry, such that single changes can lead to a particular high activity … could be a reasonable number if you are talking about a plant and a microbe interacting very stably. So it makes … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… ag[riculture] and I really liked – I became interested in plant disease in part because of what happened in my Peace … parasite you really can’t grow well. You have to have it in cell culture. So we are going to see if we can express that … alone – I’m interested in pathogens. It’s just never a single microbe. And we have several recent papers and are …

… and SIO. Oh, I should say what those are. Brad: What’s SIO, for all those listeners out there? Dan: Scripps Institution … chemicals that are coming out of organisms, whether it be a plant or from the bottom of the ocean, from a sponge, or a … of, better understand fundamentally what’s going on in the cell as it responds to its ocean environment. And as we …

… discovery at the DOE Office of Science through high performance computing (HPC) and data analysis.  The DOE Systems … the Letter of Intent; rather proposals are submitted in a single step. … The researcher then submits a proposal for … more customized analysis, the JGI also participates in publication of results. … Submission … More on Sequencing …

The Facilities Integrating Collaborations for User Science (FICUS) initiative was established in 2014 … the expertise and capabilities of multiple Department of Energy Office of Science National User Facilities into their … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical …

Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

… we want a chemist to study the ocean. And I didn’t find a single job advertisement. But one day, I decided to really … local marine environment. I went out and picked up marine plants, I picked up animals. And I asked the simple … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, …

… automation, and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics.   … Deputy …

… patterns in the  Arabidopsis root, profiling nearly 100,000 single root cells and combining the information with … the largest integration of single-cell datasets in plants and provides a foundation for still larger efforts in … with resulting reports and a  perspective article . Publication: Shahan R et al.  A single cell Arabidopsis root …

Uncovering associations between plant roots and fungi that can help or harm plant host … health and diversity, which can in turn boost yields for both food and for candidate bioenergy feedstock crops. … plants (endophytes). These include genes that degrade plant cell walls and break down plant sugars. The results also …

… enduring 90-year legacy of team science—bringing science solutions to the world—and to effectively fulfill the JGI’s … ecosystem. Their trust hinges on sustaining our record of excellence and respect, and for principles of integrity, safety and reliability. As …