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… pathways, which led her to a successfully funded JGI CSP project. And we also got to talk about work at her … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that … a thioesterase. And so that thioesterase at the end of this large multimodular protein allows for release from the DNA, …

… the deployment of computational workflows at peta- and exa- scales on multicore and many core architectures with the … Genomes (IMG) data management system … As part of this project, pairwise average nucleotide identities (ANI) and … distribution of microbial genome and microbiome datasets sequenced at the JGI. IMG/M is also open to scientists …

… to DOE for final approval.  Following DOE approval, project managers negotiate project specifics with PIs … the completion of a project, the JGI makes the assemblies, gene annotations, and analyses available to the community at … more customized analysis, the JGI also participates in publication of results. … Submission … More on Sequencing …

The JGI Project Management Office carries out a number of activities … Project design with Principal Investigator Providing a general orientation to JGI systems to Investigators … access your data, share with collaborators, and coordinate publication with JGI scientists. Synthetic DNA constructs …

… and multidisciplinary nature of DOE mission science projects, this initiative aims to encourage innovative … A Letter of Intent is required. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical …

… and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary … squares are depictions of what are called domains within a larger protein. And so each of those domains is sort of like … we need people from outside of the JGI to come to us with projects that will help us actually drive this strategic …

Genome Institute provides advanced genomic capabilities, large-scale data and professional expertise to support the … the completion of DOE’s commitment to the Human Genome Project , the University of California, which manages … are at the core of many environmental processes, and the genetic makeup of microbial species and communities forms …

… the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … in partnering with us, we want to hear from you. We have projects in genome sequencing, DNA synthesis, … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… databases and analytical tools for all JGI sequencing projects. In 2021, the JGI launched the Data Portal to … system. … IMG/PR is a plasmid genome resource featuring the largest collection of plasmids automatically identified from … host taxonomy, conjugation potential, antibiotic resistance genes, and ecosystem information. … The IMG/VR database …

To researchers searching for sequences of RNA viruses in large data sets, their work may be akin to finding a single … than 5,000 data sets of RNA sequences (metatranscriptomes) generated from diverse environmental samples around the … viruses,” said Simon Roux , a JGI scientist and one of the project co-leads. “But same as DNA viruses, RNA viruses …

… single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better … We will eventually construct a bioenergy plant single-cell atlas comprising Sorghum, Switchgrass, and Brachypodium … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …