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… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … DNA modifications (epigenome).  In  Nature Ecology & Evolution , a team led by Robert Schmitz at the University … between genome-wide 5mC abundance and the abundance of specific 5mC methyltransferase (MTase) variants. Using new …

… schedule. This should be coming out on the first Thursday of the month, just like I promised. Now I just have to make … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that oftentimes turn … Purdue, about bacterial signaling molecules and regulation of biosynthetic pathways, student mental health, and getting …

… gene families involved in adaptations seen in later plant lineages. The team found that some of the adaptation … in flowering plants, or angiosperms, suggesting they are evolutionarily conserved across plant lineages. They … a resource that associates plant’s genetic variants with specific adaptation mechanisms they had identified. For …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … They’re at the base of the animal kingdom, in terms of evolution. Because they’re sitting there, they tend to have … sequence into an antibiotic that kills bacteria through a specific mechanism. Or whatever that peptide might be doing. …

… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the biological … into practical applications, including sustainable biofuels, biomaterials, natural products, and environmental …

… Below is a brief description of the process needed to prepare and ship samples for … sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been the rate-limiting … step for many projects at the JGI. The quality of the starting material is one of the greatest predictors …

… while, but Natural Prodcast is back again for another round of episodes. If you stick around for the next few months, … you may have hear over there, with a few more questions specific to secondary metabolites. I hope both versions are … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … chance to deliver this molecule – very toxic molecule – to specific disease cells. So, the very first compound was … among many, many major discoveries since the genomic revolution, to me, as a natural part chemist for microbial …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … systems are also everywhere – that there are some very specific patterns and shared DNA across all of these things. … and another system. There should be. I mean, there’s some evolution that happened. But, you know, bacteria don’t leave …

… joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to expand the JGI’s portfolio of user companies. Now the Department of Energy is uniting … including User Facilities like the JGI, through its Genesis Mission. Launched in 2025, the initiative aims to …

… Celebrating 25 years of genomics research 2022 marked the JGI’s 25th anniversary. We revisited a number of notable achievements that showcase our collaborations and … the JGI’s 25th anniversary, the JGI mural references dozens of iconic JGI contributions to advancing the frontiers of …