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… fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better … strains, whereby they can modulate host metabolism, gene expression and phenotype. We have recently identified …

… critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at improving our collective … While an ever-increasing number of phage and virus genomes have been assembled and reported from metagenomes, …

… Biology is currently experiencing a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational technology … 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science …

… growth, provide critical advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and communication. Studying … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to …

… to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … applications, including sustainable biofuels, biomaterials, natural products, and environmental solutions, fostering a …

… starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or … and Appendix. An Appendix identifies the type of work or specific proposal to be covered under the Agreement. The … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, Biodesign and pathway engineering Mass spectrometry based metabolomics Below is a … Fungal Minimal Draft Lower coverage short-read whole genome shotgun sequencing Assembly, annotation ( Mycocosm ) …

… The Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also … technology in order to enhance the quality of single-cell genomes and directly link functional information with …

… this identification, metabolomics enables functional genome annotation, improves understanding of the role small … products At JGI, in-depth molecular profiles are generated for metabolites extracted from a variety of … as different types of environments (e.g. soil, lake).  A wide range of metabolites are identified using LC-MS/MS …

…   Our Sequencing Technologies Group is well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our users. … profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a …

… Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology teaching … genomic resources empower students through isolation and genome sequencing of new fungal species.  Students collect fungi, sterilize tissue, isolate genes and more. The metadata then goes into iNaturalist. …