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… Hey, Alison Takemura: Hey, Dan. Dan Udwary: Today we’re going to talk to Kate Duncan. And Kate is– I should ask, you … I was imagining some massive contraption for amplifying genes. I wasn’t really sure what actinobacteria were. Dan … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … function to a particular producing organism in the context of a clearly defined ecological interaction. So it’s …

…   Our Sequencing Technologies Group is well-integrated across JGI departments to ensure a robust … sequencing pipelines. This includes advanced sample management (quality assurance/quality control [QA/QC]), … large-scale liquid handling automation, and sequence analysis. …

… fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better …

… The User Support Analysis group provides computational analysis for new technology development and JGI user science … We perform analysis for diverse experiment types, with main focus areas being genome variation, transcriptomics and …

… Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology teaching … species.  Students collect fungi, sterilize tissue, isolate genes and more. The metadata then goes into iNaturalist. … Myco-Ed has:  ~50 lineages selected for sequencing 16 genomes released 20 members from 15 institutions 300+ …

… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by … parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and … While an ever-increasing number of phage and virus genomes have been …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such … in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated … Phylogenetic diversity estimates show that the gap between …

… strengthens -omics technologies at the JGI by identifying the actual molecules present in an environment that … based methods in combination with advanced computational analysis.   Overview of metabolomics products At JGI, in-depth molecular profiles are generated for metabolites extracted from a variety of …

… FY2025 Spending Profile The JGI is funded primarily by the DOE Office of … Biological and Environmental Research (BER), a program within the DOE Office of Science. …

… provide advanced genomic capabilities, large-scale AI-ready data and professional expertise to support the global research community in studies of complex biological and environmental systems. We optimize our service to the community through … of biological processes that enable cost-effective energy generation and innovative materials production. Through …