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… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a podcast about natural … If we are only interested in that final product, which is completely potent and specific to the target we’re thinking … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I … in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … called Ecopia was talking about a gene cluster a week. They completed a gene cluster per week. And that really got me …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to only three phyla. The Woyke group uses single-cell …

… in natural products right. There’s many different avenues toward chemistry. But that’s kind of where I had you. How … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … genome sequence, in about 40% of the genome the genes were completely unidentifiable. You had no idea what they were …

… The Joint Genome Institute and the Molecular Foundry have launched a … call . This represents a unique opportunity for researchers to request the capabilities and expertise of both national user facilities in one research proposal.  … Access to the Molecular Foundry and use of JGI capabilities is …

… DAN UDWARY: Hey everyone. Welcome back to Natural Prodcast. This continues the series of interviews … enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … or something, but they confirmed that it had just been completely consumed. DAN UDWARY: Grad students need calories …

… Undergraduate Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology teaching labs. The purpose of the program is to: train students and professors in laboratory techniques … genomic resources empower students through isolation and genome sequencing of new fungal species.  Students collect …

… DAN: All right. Welcome back to Natural Prodcast. I did it. I’m keeping to my schedule. … exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … with known receptors, but we also have ones that are completely their own cluster. And so we're hypothesizing …

… global nutrient cycling, however they do so under strong constraints exerted by viruses. Research in the viral genomics … group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host … and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts of viral infections. The …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… DAN UDWARY: Hey, everyone! Welcome to the “Self Promotion Episode” of Natural Prodcast. A … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever … trying to understand that system is just not possible from– completely understanding the system is not possible from the …