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… in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … called Ecopia was talking about a gene cluster a week. They completed a gene cluster per week. And that really got me …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is targeted at environmental … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …

… The JGI is involved in efforts to integrate data in support of new research questions that span domains. We also work with our partners to build infrastructure in support of new analysis techniques.  Notice Data Portal files will be inaccessible July 22–July 24 for computing upgrades . We regret any inconvenience. …

… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … genome sequence, in about 40% of the genome the genes were completely unidentifiable. You had no idea what they were …

… The Joint Genome Institute and the Molecular Foundry have launched a … for researchers to request the capabilities and expertise of both national user facilities in one research proposal.  … challenges in the sourcing, recovery, and utilization of critical minerals and materials. The proposal submission …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … or something, but they confirmed that it had just been completely consumed. DAN UDWARY: Grad students need calories …

… Undergraduate Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology … genomic resources empower students through isolation and genome sequencing of new fungal species.  Students collect … Myco-Ed has:  ~50 lineages selected for sequencing 16 genomes released 20 members from 15 institutions 300+ …

… exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … with known receptors, but we also have ones that are completely their own cluster. And so we're hypothesizing …

… global nutrient cycling, however they do so under strong constraints exerted by viruses. Research in the viral genomics … group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host … involves both experimental and computational exploration of uncultivated viral diversity, characterization of …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …