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… in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … called Ecopia was talking about a gene cluster a week. They completed a gene cluster per week. And that really got me …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from candidate phyla, major … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …

… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … genome sequence, in about 40% of the genome the genes were completely unidentifiable. You had no idea what they were …

… The Joint Genome Institute and the Molecular Foundry have launched a … for researchers to request the capabilities and expertise of both national user facilities in one research proposal.  … challenges in the sourcing, recovery, and utilization of critical minerals and materials. The proposal submission …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … or something, but they confirmed that it had just been completely consumed. DAN UDWARY: Grad students need calories …

… Undergraduate Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology … techniques and data analyses compile original data for improving fungal genomic resources empower students through isolation and genome sequencing of new fungal species.  Students collect …

… exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … with known receptors, but we also have ones that are completely their own cluster. And so we're hypothesizing …

… global nutrient cycling, however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host … While an ever-increasing number of phage and virus genomes have been assembled and reported from metagenomes, …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… Breaking Bad, I guess. But no, you trained me in how to genome mine, so thank you for that. And you had to put up … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever … trying to understand that system is just not possible from– completely understanding the system is not possible from the …

… for researchers to request the capabilities and expertise of both the Joint Genome Institute and the Molecular Foundry in one research … provides customized analysis, the JGI also participates in publication of results. Go here for additionial information, … as needed), and the work plan is written into a Statement of Work document. …

… know, I’m here to find a job. I would like to do something completely new. And that is to begin to study the organic … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …