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Natural Prodcast Episode 18: A CSP Primer
… Menaka Wilhelm, who is the host of JGI’s other podcast, Genome Insider . If you’re a Genome Insider listener, then … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we … process. So it’s really important to submit everything most completely. And then, there’s different sections that …
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Secondary Metabolites Program
…   The JGI’s Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and … Program targets the vast and underexplored reservoir of secondary metabolites produced by bacteria, fungi, algae …
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Frequently Asked Questions: Project Management
… Eukaryotic projects: Kerrie Barry or Vivian Ng Prokaryotic projects: Tijana Glavina del Rio , Danielle Graham , or Miranda Harmon-Smith DNA Synthesis projects: … You can visit the Products & Offerings section of our website for more details, including a … The majority of JGI projects come from the user community. Find out about …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… Breaking Bad, I guess. But no, you trained me in how to genome mine, so thank you for that. And you had to put up … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever … trying to understand that system is just not possible from– completely understanding the system is not possible from the …
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Single Cell Research Group
… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …
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Natural Prodcast Episode 16: Marcy Balunas
… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … genome sequence, in about 40% of the genome the genes were completely unidentifiable. You had no idea what they were …
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Mining New Frontiers: The Critical Minerals and Materials Joint Call
… The Joint Genome Institute and the Molecular Foundry have launched a … for researchers to request the capabilities and expertise of both national user facilities in one research proposal.  … materials. The proposal submission deadline is March 31, 2026 .  … free of charge, including data such as fully annotated genome assemblies or differential gene expression results. …
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DOE Metrics
… (Trillions) Operating Hours Goal  Actual Total*   Actual % of Goal   Goal (hours)**   Actual Total   Actual % Goal   FY … = 91 days; Actual Operation = 24 days due to significant sequencer downtime related to the shelter-in-place. ††† … developments for improving microbial, metagenomic, or plant genome assemblies. [Download PDF] Q2 – Report on progress …
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Natural Prodcast Episode 22: Alison Narayan
… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … or something, but they confirmed that it had just been completely consumed. DAN UDWARY: Grad students need calories …
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Natural Prodcast Episode 21: Elizabeth Parkinson
… exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … with known receptors, but we also have ones that are completely their own cluster. And so we're hypothesizing …
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Viral Genomics Group
… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by viruses. Research in the viral genomics … group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host …
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Natural Prodcast Episode 8: Eric Schmidt
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …
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