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I’m committing to it, and you all can hold me accountable and yell at me if I slip again. My JGI coworkers are … Very familiar with working actinomycetes. We can also genetically manipulate them. We can do strain improvements. … of microbial sequences. So let’s say you’re interested in improving a lead compound that you’ve discovered from …
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… looking at that I’m a very visual person. So, when we make genetic mutants in a fungal isolate, I can see something … Yeah, okay. Of course. Fungi have a larger genome. The genetics was slower to begin with. So transformation, or … were transformed. So I wasn’t even thinking of molecular genetics of finding genes when I first started out, because …
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Udwary: Yeah. Kate Duncan: So they’re also incredibly adaptable. I think there has been some examples of real … at the chemistry produced by microbes, they’re pretty adaptable to other organisms. And we’ve done that with … of CEOs, professors, and the kind of decision making table– the data is still very unequal. Dan Udwary: Yeah. …
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… to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied … descendants of ancestral genes are constructed at key phylogenetic nodes. These families allow easy access to …
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… viral genomes and occasionally remembering to document his code. At JGI, he develops tools for viral discovery and … "spicy messenger RNA", and that somewhere in the mess of genetic sequences lurks the next cool virus – if only our code would stop crashing... …
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… are there. And so at a certain point, they're more detectable to the other organisms and they-- I don't know hear … that's remarkable, and then you have the capability and the flexibility to really alter residues and then also look to …
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… how microbes can colonize plant roots, focusing on genetic components required for effective colonization. In …
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