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… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that … origins and mechanisms of pathogenesis . Science. 2006 Sep 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …

… I have been in – working in secondary metabolism for almost 20 years now. Which when I did the math, that was a surprise … drug. It was the largest selling drug back in the early 2000s for cancer. You know, a billion dollar drug. But where … got the podcast. If you have a question, or want to give us feedback, tweet us @JGI, or to me @danudwary. If you want to …

… account? Or do you and your lab focus mainly on what can we feed this and what can it actually turn over? ALISON … has to do with the mechanism. And so these enzymes use O2, and one of those oxygen atoms gets incorporated into our product, and one of those oxygen atoms from O2 ends up as a molecule of water. DAN UDWARY: Mhm. So …

… As a National User Facility, the JGI serves more than 2,500 users that predominately come from the public sector: … by industry. When Director Nigel Mouncey joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to … Science Program, the JGI sequenced and characterized 270 genomes of the Clostridium genus for LanzaTech, …

… in their environment and eating them. They’re filter feeders that have a really important role on the reef and … got the podcast. If you have a question, or want to give us feedback, tweet us @JGI, or to me @danudwary. If you want to …

… 10.1038/s41579-020-0381-4 10.1038/s41396-020-0637-z 10.1038/s41477-024-01666-3 10.1016/j.celrep.2023.112676 10.1016/j.devcel.2022.01.008 … Selected Publications …

… seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … do research. And it moved me to ask a simple question. In 1929, Alexander Fleming discovered a molecule called …

… Development of cell-free based expression platforms: Only 10-20% of BGCs are expressed under standard laboratory …

… acids (aa) in size, half that of previously known class 2 CRISPR enzymes that are typically 950—1400 aa. They were initially identified by searching for Cas12d homologs across IMG/M’s assembled metagenomic data. It … out that some of these were shorter than the typical Cas12d proteins and were also found next to cas1 genes. Further …

… Yeah, that’s right. We were postdocs together in the mid 2000s, I guess. You were working for Brad Moore. I was … for those 50 journals. For – [it] varied -something like 20 years, and then we – I – forced the lab group to take a … got the podcast. If you have a question, or want to give us feedback, tweet us @JGI, or to me @danudwary. If you want to …

… The JGI’s Genomes OnLine Database celebrates 25 years as a vital resource for data contextualization The Science Since its launch 25 years ago, the  Genomes OnLine Database has matured from … new features like a public API and ecosystem landing page, as well as the growth of different entities,  further …