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… secondary metabolism. Welcome back. This will be episode 12 of Natural Prodcast. And it’s our conversation with Nadine … with the AntiSMASH and MIBiG projects. And I found her review in natural product reports on the evolution of genome … yes, sure, right. And yeah, so we worked on the Salinospora genomes. That was a really fun project. We had Brad on and …

… types, in which DNA-based molecules can be chromosomally integrated into a taxonomically diverse suite of microbial chassis strains for elevated opportunity for …

… have right is that central metabolism– or it’s also called integrated metabolism, by Firn and Jones, because it’s … kind of thing. In fact, if you take a look at the recent reviews where they discuss whether an antibiotic is really … it is more related to what JGI does, which is sequence genomes. And we just published last year in the Nature …

… chemistry is one. DAN: So, I’ve always known Roger as an expert in natural product structure elucidation, but more … you. Toss an email to  [email protected] , or leave us a review on Apple Podcasts or wherever you’re getting this and … to try and create an open source database of all known microbial natural products. So if you think about natural …

… capabilities, large-scale AI-ready data and professional expertise to support the global research community in … crops, enhance biomass conversion efficiency, and discover microbial pathways for producing biofuels, biochemicals, and … Critical Minerals and Materials (CMM): Genomic studies of microbial and plant metabolism reveal biological routes to …

… that can take a long time depending on how the purification goes. In order to be a drug, you also nowadays usually need … we can find more things. Turns out some of the early genomes that were sequenced for, say, Streptomyces – they … are by Jahzzar. Please help spread the word by leaving a review of Natural Prodcast on Apple podcasts, Google, …

… science including technical capabilities offered, proposal review procedures and the annual user meeting. The UEC also …

… Sequencing Program, and they worked with us to sequence two genomes. Those were of Salinospora tropica and arenicola . … looking at seaweeds, macro algae. And the list pretty much goes on. We’re looking at, now, diatoms and golden algae, … are by Jahzzar. Please help spread the word by leaving a review of Natural Prodcast on Apple podcasts, Google, …

… opportunity for researchers to request the capabilities and expertise of both national user facilities in one research … materials. The proposal submission deadline is March 31, 2026 .  … (CMMs). Click for a list of CMMs and the results of the 2023 DOE Critical Materials Assessment . While we expect …

… As a National User Facility, the JGI serves more than 2,500 users that predominately come from the public sector: … by industry. When Director Nigel Mouncey joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to … entail a competitive, proposal-based process including peer review. The process is streamlined, with defined deadlines …

… Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge … technology in order to enhance the quality of single-cell genomes and directly link functional information with … To provide additional functional insights into microbial genomes, the JGI now uses laser microdissection to …

… seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … powerful people. These were people that really controlled microbial drug discovery. And a guy like me, with no … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …