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… and show notes at naturalprodcast.com — I went a little overboard with links on this, since I’m hoping this episode … Tang at UCLA and then kind of really gained more of the bioengineering aspect with fungi, kind of going along the track … hypersaline lakes– and start comparing and contrasting systems and then also comparing to the marine environment, …

… of these really interesting molecules, oftentimes much more efficiently than we can in the lab. And so that's how I got … can turn on the natural product, say clusters or expression systems so that-- BETSY PARKINSON: Exactly. DAN: --you get … Mainly actinos. Yeah. DAN: Yeah. I mean, those are the systems that are best understood right now. So yeah. If you …

… high altitude! And a lot of us moved on to work in simpler systems, like bacteria, where we figure we can make more … nature does this. The more well-known secondary metabolism systems are the “Non-Ribosomal Peptide Synthetases” or NRPSs. These are enzyme systems that grab amino acids and stick them together to …

… . Giant viruses with an expanded complement of translation system components.” Science 356(6333): 82-85 (2017). …

… the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director Nigel Mouncey. … has already demonstrated CRAGE as a versatile engineering system that allows scientists to conduct genome-wide screens … together, microbes can be used to create compounds more efficiently than one strain could on its own.  In work …

… to the community level. The Impact Rivers are transport systems, and their health is heavily reliant on the energy … predictive watershed scale models to manage river ecosystems. One application for the information is the development of river health diagnostic systems to monitor for and identify land use or water …

… and associated viruses that all contribute to a dynamic ecosystem. We are interested in how plants self-organize, … fitness and health. This is a dynamic and complex ecosystem that includes bacteria, fungi, viruses. Resident … approach, we employ various omics technologies, strain engineering and experimental characterization methods, in …