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I didn’t know how to get towards that.  Organic chemistry doesn’t really help with getting to something other than the … local environments, and so they don’t transfer a lot of DNA back and forth, especially across species. And so then … do when you’re exploring your systems. Because I think the JGI has a little bit of a different approach. We don’t …

… in that area?   NANCY: Oh, well, I love fungi, okay, this doesn’t even have anything to use natural products … species”… he’s now found that some fungi have different ITS sequences in their genome, which might get you a little … actually, everything is funding, right, isn’t it? I thank JGI for sequencing a lot of fungi. But the thing with them – …

… state of things, and what we’re hoping to accomplish at JGI in this area. If this series of podcast episodes has … DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the proteins that … we recognize and sticking another piece in, that usually doesn’t work, or if it does work, it doesn’t work as well, …

… for the US Department of Energy Joint Genome Institute, or JGI. JGI is a DOE Office of Science User Facility located at Lawrence … – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic …

… think his energy is infectious. DAN: I’ll say up front that JGI recently started collaborating with Ben and his group to … What is beautiful for natural products is nature! Nature does this sort of – if you think of nature as a scientist, … And in DNA is all that the same molecule, just different sequences BEN: The other thing I think about JGI is, really, …

… data portal I’ve been working on with my colleagues Drew Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and … BGCs but highly fragmented, in most of the metagenome sequences that we’ve already analyzed. But that’s a whole …

… you guys. I’m trying really hard just for you. And the JGI Comms team. But mostly you. Anyway…I’m really happy … bit of entomology as well. DAN: Right. Yeah. No, yeah, Bill does it all. A lot of people I think-- well, maybe I'm … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …

The JGI Project Management Office carries out a number of activities to facilitate world-class science. DOE JGI Project Managers collaborate with users to develop … and coordinate publication with JGI scientists. Synthetic DNA constructs are also shipped at this time. Your Project …

The Synthetic Biology lab is divided into a DNA synthesis production group and a synthetic biology applications group. The DNA synthesis and assembly group: Our production group … technologies to the broader community.  We focus our efforts on integrating database mining and sequence design …

… up a tiny bit and just say what antiSMASH actually is and does. Marnix Medema: Yeah. So antiSMASH. We built antiSMASH … problem in the field, that there were many papers reporting sequences and pathways– sequence is not right to say. But of … of question have you applied them? Dan Udwary: Well, at JGI we have the Atlas of Biosynthetic Clusters . And this is …

… special way to be able to hang out with a parent who then doesn’t become your parent anymore, but has this other role … first genome sequence with you. Brad: That’s right,  Dan: JGI did it in fact. Brad: That was a magical project I … environment you mentioned, you know that they can have consequences to marine life that surrounds it, whether it be …

With collaborative user projects, the JGI’s Plant Program delves into the natural world’s … to environmental changes. The program lays the groundwork for sustainable solutions to current problems facing … discussion with the JGI Plant Genome Advisory Committee and DOE, designating a set of JGI plant genomes that are the …