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… A deep dive into microbial genomics reveals one bacterial … In the ocean’s North Pacific Subtropical Gyre, microbes tend to stay localized at different depths. But … to determine the genome structure of SAR324 cells and their gene expression, the team then sequenced community genomes …

… “Microbes underpin so much of what we see on earth in terms … have many questions about the microbial communities deep underground, and before the pandemic, they took the JGI …

… and analysis. This way, JGI users — both primary, data-generating users, as well as secondary, data-downloading … for a time-series experiment from the highly-studied Lake Mendota is told as part of a three-part series of our  … ecologist and JGI user Trina McMahon has been sampling microbes at Lake Mendota, which borders the University of …

… with 86 participants in an online workshop to harness deep learning for metagenomic data.  Metagenomic data, or … rather than single cells or isolated strains, is easy to generate, but difficult to assemble and interpret. The … researchers are utilizing deep learning to automatically generate insights from metagenomic data. In deep learning, a …

… I think for Natural Prodcast, I think the question that generally comes up that people come to me asking like is– … more functional questions. For example, we can synthesize a gene and then figure out what it might be doing through some … where smaller proposals may be a fit. Still not 20 many microbes. We still we work in plates, right? We’re a high …

… Lake Mendota sits right next to the University of Wisconsin, … Madison. And Trina McMahon's lab has been sampling the microbes of that lake for over 20 years, to understand how the freshwater …

… America brought to the UK? ROGER:  Yeah, it’s difficult to generalize, of course, but I felt overall that the British … my perspective, JGI has a large database of biosynthetic gene clusters and biosynthetic gene cluster fragments, and all kinds of other crazy things. …

… The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in environmental processes … lifestyles found in the Antarctic lakes and offers a genetically-tractable model system that could help … first member of the Archaea isolated from Deep Lake, the coldest place on Earth known to support life, and previously …

… Streptomyces are nature's chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay … activate multiple chemical production pathways. By tracking gene activity and chemical output over time, the team mapped … users can leverage to create a more complete picture of how microbes control useful chemistry in other organisms.  …

… and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary … developed to the point that you could understand the genetics of secondary metabolism, it became possible to do … proteins that are enzymes that are doing the reactions to generate secondary metabolites. ALISON: Sounds easy enough? …