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Axel Visel
… in 2004 from the Max Planck Institute in Hanover, Germany, where he developed novel tools for large-scale in situ gene expression analysis in … (2015).  Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions. Cell 161, …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
With a new methodology, scientists are now getting more … the earth, but most species do not grow easily in the lab. To access the genomes of uncultured  microbes , scientists … with PTA, compared to <30% complete when studied with MDA. With the introduction of PTA, JGI users can get more …
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Viruses Reprogram Cells into Different Virocells
State University and the University of Michigan studying how virus infections cause significant metabolic changes in marine microbes, the answer is no. They refer to the infected microbial cells as virocells, a change in … Research and operated under Contract Numbers DE-AC02–05CH11231 (JGI) and DE-AC05–76RL01830 (EMSL). This work was funded …
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JGI@25: From Life at the Extremes to Editing Genomes
In honor of the JGI&#039;s 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great science that will help solve energy and … for Some Type V CRISPR-Cas Systems Mol Cell. 2020 Aug 6;79(3):416-424.e5. doi: 10.1016/j.molcel.2020.06.022. Wright AV …
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High Five: Celebrating the JGI-UC Merced Genomics Internship Program
More than 20 UC Merced students have contributed to the research of 13 JGI scientists since the program’s inception. In 2014, JGI’s Zhong Wang and Science Programs Deputy Axel Visel teamed with …
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An Automated Tool for Assessing Virus Data Quality
… and identified from environmental samples (metagenomes). However, the quality and completeness of metagenome-assembled … have now developed CheckV (pronounced “Check-Vee”) to help researchers assess and improve the quality of … U.S. Department of Energy under contract no. DE-AC02-05CH11231. This work was also supported the grant #2016/23218-0 …
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Making a Lichen Together
For the first time, a team analyzes the transcriptomes of a lichen fungus and alga to understand their … a superorganism: one being that is actually comprised of two (or more) participants. One is a fungus (usually … by a DOE-Biological Environmental Research grant No FWP 61327 to FRC and PL (for RNAseq). The work at the Joint Genome …
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Training the Next Generation of Talent
New Graduate Internship Program Builds Bridges Between DOE … was back on campus at the University of California, Merced to start orientation as a first-year graduate student in the … which is best for the task at hand. “There are at least 30-40 programs and it is not clear which are the best to …
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