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Better Genome Editing for Bioenergy
… of the genes in a lipid-prolific yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to … at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User Facility. Y. lipolytica … genes were essential to  Y. lipolytica . They identified 1,377, or 17.5 percent, of  Y. lipolytica ’s genes to be …
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Operating Expenses
… FY2025 Spending Profile The JGI is funded primarily by the DOE Office of Biological and …
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Adopt-A-Genome
… In this episode, undergraduates adopt genomes that the JGI sequenced, but never published in the literature. These … (JGI) and Matt Escobar (California State San Marcos) about how the Adopt-A-Genome project got started. Plus, Kalyani Maitra (California State Fresno) and two …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… now available to the global research community able to not just analyze but also create DNA sequences mimicking an array … sequences based on the principles it learns from the data about genetic structure — carrying with it the potential … machines. You’d go find the cash converter box, feed it a $1, $5 or $10 bill and receive a set amount of tokens, …
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JGIota: Looking Back at Sequencing for Soybeans
… that could boost biofuels and fertilize fields. So in 2010, the JGI helped publish the original genome sequence for … able to look into soybean’s strengths – along with a fungus that threatens this important crop. Hear more about that work from researchers Gary Stacey (University of …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… enzyme family evolved across 90 species. “One unique thing about this work was our focus on all the kingdoms, including animals, plants, bacteria, … enzymes across 90 species. They queried the genomes of 15 species from each of six kingdoms: eubacteria, archaea, …
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Extracting the Secrets of Secondary Metabolites
… combo helps further demystify biosynthetic gene clusters.  The Science Microbial secondary metabolites, those … and other industries — yet there’s still so much about them we don’t know.  Unlocking the power of secondary … in overcoming this obstacle when it hit the scene in 2019. Now, that power is poised to grow exponentially by …
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From Intern to Published Scientist: The Journey of a JGI-UC Merced Intern
… ultimate achievement. To get to this point requires rigorous research, written skill, above all else, determination. … in this publication during her summer internship in 2018. She selected one of the projects posted by JGI fungal … Grigoriev at the JGI strongly influenced her perspective about what it means to be a scientist. “To see how team …
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Honey Bee Gut Microbiota Divvy Up Dinner
… of the National Academy of Sciences . The team focused on the dominant bacterial clades shared between honey … pollen’s pectin and hemicellulose are degraded mainly by just two clades:  Gilliamella,  which mostly resides in the bee’s ileum, a structure analogous to the human small intestine; and  Bifidobacterium,  …
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Notes on the Microbial Diversity of Puerto Nuevo’s Coastline
… snails, UC Merced graduate student Sabah Ul-Hasan and alumnus of the JGI-UC Merced Genomics Internship Program, first sampled the area in summer 2016.  She described the microbial diversity patterns of … Nuevo is, historically, a fishing town and we know little about its coastal microbial ecology. We also know little …
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Marine Microbe Contains Multitudes
… different lifestyles. The Science The bacterium SAR324 is unusually cosmopolitan. In the ocean’s North Pacific … Boeuf and colleagues set sail on research cruises in 2015 and 2016. At Station ALOHA , site of the 30-years-long … at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Gotta Catch 'Em Gall
… called galls.  In this episode, hear from Kasey and Patrick about how this project unfolded, and how they worked with the JGI's metabolomics program to find out more about these weird little pods. …
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