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… time of publication, it is the largest repository of BGC sequence data from over 1.3 million publicly available … using multiple commonly used sequence analysis tools is a means of expediting BGC and biosynthesis … and metagenome data.   The SMC ( smc.jgi.doe.gov ) is designed with two main objectives. First and foremost, it is …

… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … increased the number of known high quality virophage genome sequences 10-fold through computational approaches. By … of 328 “high quality” (based on completeness) diverse new virophage genomes containing all four core genes. These …

… to energy, are made up heavily of sphagnum mosses.  New research identifies sex chromosomes in the plant and … approximately one-third of the world’s soil carbon. The process to harvest energy-generating peat from these boggy … Laboratory, and the HudsonAlpha Institute for Biotechnology sequenced sphagnum  genomes from plants selected by a team …

… beam — worse, they didn’t even know how big the room is.  A new study  published online Oct. 11, 2023 in  Nature … the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists … those with pivotal applications in biotechnology, such as DNA editing enzymes.” Leveraging Protein Families in a New …

… can whip up dozens of complex natural products, including new ones. The Impact In the past, natural products have been … natural products, O’Malley and her team plan to use genetic tools to boost production and isolate the compounds. Although what … Collaborative Science Initiative and used resources at the DOE Joint Genome Institute and the Environmental Molecular …

… small, with mini genomes to match. As a result, they cannot process all of the chemicals they need to survive. To fill … are difficult to study in the lab. Metagenomics provides new views of these relationships.  Recently , researchers … use CRISPR-Cas systems to recognize and remove invaders’ DNA from their own genomes. One of these systems, the …

… Take a virtual tour of the IGB, home of the DOE Joint Genome Institute. To navigate virtual tours of … zoom in and out. 1st floor 2nd floor 3rd and 4th Floors The JGI mural on the 3rd floor whimsically references dozens of iconic JGI contributions to advancing the frontiers of …

… is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which … (2017). Woyke T . & Rubin E.M. Evolution. Searching for new branches on the tree of life. Science. 346:698-9 (2014). … and genomes from cow rumen. Science 331, 463-7 (2011). Newton I.L., Woyke T ., Auchtung T.A., Dilly G.F., Dutton …