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An Automated Tool for Assessing Virus Data Quality
… (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … to help researchers assess and improve the quality of metagenome-assembled viral genomes . The Impact The microbes that play key roles in cycling nutrients such as …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… A special issue of Synthetic Biology celebrates research enabled by the JGI … and synthesis work. This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … on thiolases, a superfamily of enzymes found only in microbes, which make carbon-carbon bonds. This ability is …
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What Happens Underground Influences Global Nutrient Cycles
… for User Science (FICUS) program, two Department of Energy (DOE) Office of Science national user facilities—the  … particularly, what happens in the rhizosphere where plants, microbes and soil interact below the ground, influencing the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director … advantage of their joint metabolisms. Because, together, microbes can be used to create compounds more efficiently …
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Tracing the Evolution of Shiitake Mushrooms
… New genomes highlight the diversity of white rot fungi in the genus Lentinula   The Science … Shiitake mushrooms get their name from the same place they often source their nutrients — the shii tree, a Japanese relative of the oak. These fungi are part of the genus Lentinula, …
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How Filamentous Fungi Sense Food
… . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to … N. crassa is the model organism for filamentous fungi, all of which contain a wide array of plant cell-wall degrading enzymes (PCWDEs) that allow …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… JGI-led team significantly expands the global diversity of large and giant viruses. While the microbes in a single drop of water could outnumber a small city’s population, the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at Lawrence …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… As part of the JGI’s 25th anniversary celebration, the 2022 Annual … sequencing for the Human Genome Project out to the future of the institution. Their talks shed light on how the JGI … currently works to support understanding of plants, microbes and environmental communities that have relevance …
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A Grass Model to Help Improve Giant Miscanthus
… Miscanthus  sequence offers insights into benefits of polyploidy and perenniality. The Science A reference … grass Miscanthus sinensis has been published. Analysis of the genome sequence also provides insights into how the … Innovation, which is supported by the U.S. Department of Energy, Office of Science, Office of Biological and …
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JGI@25: Building a Better Bean
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … solve energy and environmental challenges. While a hill of beans may not seem to amount to much, the common bean …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… characteristics — creating many different ways of processing nitrogen. To boost crops more efficiently in … — they rely on enzymes that have been evolving for billions of years. However, these enzymes are often loosely understood, leaving potential targets for crop …
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Calculating the Costs of Multiple Switchgrass Gene Copies
… A collaborative team led by researchers at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology (HudsonAlpha), and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, has discovered that the …
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