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Igor Grigoriev
… Grigoriev joined the JGI in 2003, following his postdoctoral training at UC Berkeley and work in the pharmaceutical … of California, Berkeley. He contributed to the Human Genome Project and led annotation and analysis of diverse eukaryotic genomes, from protists to plants. In 2009, he launched the …
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Virus Discoveries that Keep Getting Bigger
… Sequence-based studies — from metagenomics to single-cell work — have … Nucleocytoviricota , these giant viruses boast larger genomes than many bacteria. Until recently, understanding of … viruses in sequence data is read-mapping: using giant virus reference genomes to search for giant viruses in metagenomic …
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JGI announces 2024 Functional Genomics awardees
…   Each year, the JGI accepts proposals for state-of-the-art functional genomics … and omics capabilities to enhance understanding of gene and genome function. Tapping into these functions allows …
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and … to technical limitations and the sheer complexity of plant genomes. Now, with improvements to DNA Affinity Purification … in  Nature Plants  on July 15, researchers have developed multiplexed assays — experimental techniques that allow …
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Mindfully Moving JGI
… JGI is in the process of shifting its operations from Walnut Creek to the heart of the Berkeley Lab … Walnut Creek and deciding on what was essential. There were multiple waste streams to consider, including unneeded … that would actually go to the landfill. Sorting required multiple speedpaks – large boxes with nearly a cubic yard of …
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From Sample Shipments to Sequences – A Tour of the JGI’s Sequencing Pipeline
… Every year, the JGI sequences around 35,000 samples — from plants, algae, bacteria, … Most of those researchers send their samples in from afar, without ever hearing much about the sequencing lab. So …
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JGI announces 2023 CSP Functional Genomics awardees
…   Each year, the JGI accepts proposals for state-of-the-art functional genomics … and omics capabilities to enhance understanding of gene and genome function.  Below find a list of the six researchers …
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JGI announces 2025 Functional Genomics awardees
… [ Pictured from left: [Above] Hao Chen, Matthew Cope-Arguello, Theophilus Olufemi … and omics capabilities to enhance understanding of gene and genome function. Tapping into these functions allows …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… Team develops a computational pipeline to sift and … Information, and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … cell, RNA viruses store their genetic information in RNA without a DNA stage. “I would argue RNA viruses globally are …
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Decoding Yellowstone’s Microbial Mats
… Life as we know it wouldn’t exist without cyanobacteria; they began oxygenating Earth over two billion …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… Sequencing technology has changed dramatically over the last  25-plus years since … for researchers to get a close look at more ecosystems and organisms than ever before. In 2006, the JGI produced 33 … to enable large-scale analysis. The story of a massive metagenome assembly for a time-series experiment from the …
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Georg Rath
… Mr. Rath has been leading the Systems Infrastructure Team at the JGI since 2020. … built by his team is unbureaucratic and driven by code, without putting humans in the loop. He is a big proponent of …
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