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Doubling Down on Known Protein Families

… (IMG/M) database, they successfully crafted the Novel Metagenome Protein Families (NMPF) Catalog. “We can now … there has been no real analysis of protein families from metagenomes per se.” Recently, other research teams have … pivotal applications in biotechnology, such as DNA editing enzymes.” Leveraging Protein Families in a New Way The …

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Identification of novel biomass‐degrading enzymes from genomic dark matter: Populating genomic sequence space with functional annotation

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Expression of macromolecular organic nitrogen degrading enzymes identifies potential mediators of soil organic N availability to an annual grass

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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways

… called terpenes. Terpenes are made via a tangled network of enzymes in plants. To better pinpoint the biosynthetic … projects in our group. It’s enabled us to accelerate gene, enzymes, and pathway discovery approaches and provided the … and then basically exploded, so that the molecules and enzymes that were once trapped inside are now, still …

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In depth metagenomic analysis in contrasting oil wells reveals syntrophic bacterial and archaeal associations for oil biodegradation in petroleum reservoirs

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Position-Specific Metabolic Probing and Metagenomics of Microbial Communities Reveal Conserved Central Carbon Metabolic Network Activities at High Temperatures

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Metagenomic Analysis of Subtidal Sediments from Polar and Subpolar Coastal Environments Highlights the Relevance of Anaerobic Hydrocarbon Degradation Processes

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Integration of Metagenomic and Stable Carbon Isotope Evidence Reveals the Extent and Mechanisms of Carbon Dioxide Fixation in High-Temperature Microbial Communities

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Phylogenetic and Functional Analysis of Metagenome Sequence from High-Temperature Archaeal Habitats Demonstrate Linkages between Metabolic Potential and Geochemistry

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Decomposing a San Francisco estuary microbiome using long-read metagenomics reveals species- and strain-level dominance from picoeukaryotes to viruses